# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4461925 | 30 | INH | = | 95 | % | ALA4704020 | % | Homo sapiens | |||
2. | ALA4461925 | 30 | IC50 | = | 39 | uM | ALA4704019 | 4.41 | nM | Homo sapiens | ||
3. | ALA4461925 | 30 | IC50 | = | 30 | nM | ALA4704018 | 7.52 | nM | Mus musculus | ||
4. | ALA4461925 | 30 | IC50 | = | 22 | nM | ALA4704017 | 7.66 | nM | Homo sapiens | ||
5. | ALA4461925 | 30 | IC50 | = | 74 | nM | ALA4704015 | 7.13 | nM | Mus musculus | ||
6. | ALA4461925 | 30 | IC50 | = | 48 | nM | ALA4704014 | 7.32 | nM | Homo sapiens | ||
7. | ALA4461925 | 30 | IC50 | = | 22 | nM | ALA4312827 | 7.66 | nM | Homo sapiens | ||
8. | ALA4461925 | 30 | IC50 | = | 48 | nM | ALA4312826 | 7.32 | nM | Homo sapiens | ||
9. | ALA4461925 | 30 | IC50 | = | 30 | nM | ALA4312825 | 7.52 | nM | Mus musculus | ||
10. | ALA4461925 | 30 | IC50 | = | 74 | nM | ALA4312824 | 7.13 | nM | Mus musculus | ||
11. | ALA4461925 | 30 | IC50 | = | 39 | uM | ALA4312823 | 4.41 | nM | Homo sapiens | ||
12. | ALA4461925 | 30 | INH | = | 95 | % | ALA4312822 | % | Homo sapiens | |||
13. | ALA4461925 | 30 | Ratio IC50 | = | 4 | ALA4312821 | ||||||
14. | ALA4461925 | 30 | Ratio IC50 | = | 2 | ALA4312820 | ||||||
15. | ALA4461925 | 30 | logD | = | 1.96 | ALA4312819 | ||||||
16. | ALA4461925 | 30 | solubility | = | 0.31 | mg/ml | ALA4312817 | ug.mL-1 | ||||
17. | ALA4461925 | 30 | AUC | = | 4.76 | mg.hr/L | ALA4312818 | ng.hr.mL-1 | ||||
18. | ALA4461925 | 30 | Cmax | = | 1.59 | mg/L | ALA4312816 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
19. | ALA4461925 | 30 | CL | = | 10.5 | ml/min.kg | ALA4312815 | mL.min-1.kg-1 | ||||
20. | ALA4461925 | 30 | t1/2 | = | 2.5 | hr | ALA4312814 | hr |