| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4462110 | (S)-38 | INH | = | 122 | % | ALA4423294 | % | Homo sapiens | |||
| 2. | ALA4462110 | (S)-38 | F | = | 45 | % | ALA4423323 | % | ||||
| 3. | ALA4462110 | (S)-38 | beta t1/2 | = | 0.3 | hr | ALA4423315 | hr | ||||
| 4. | ALA4462110 | (S)-38 | CL | = | 32 | ml/min.Kg | ALA4423312 | mL.min-1.kg-1 | ||||
| 5. | ALA4462110 | (S)-38 | Vdss | = | 0.8 | L/Kg | ALA4423309 | L.kg-1 | ||||
| 6. | ALA4462110 | (S)-38 | CLH | = | 20 | uL/min | ALA4423308 | uL/min | ||||
| 7. | ALA4462110 | (S)-38 | Fu | = | 34 | % | ALA4423307 | |||||
| 8. | ALA4462110 | (S)-38 | Activity | 0 | ALA4423306 | Toxic | Rattus norvegicus | |||||
| 9. | ALA4462110 | (S)-38 | Activity | 0 | ALA4423305 | Toxic | Rattus norvegicus | |||||
| 10. | ALA4462110 | (S)-38 | pEC50 | < | 5 | ALA4423287 | nM | Homo sapiens | ||||
| 11. | ALA4462110 | (S)-38 | INH | = | 67 | % | ALA4423303 | % | Homo sapiens | |||
| 12. | ALA4462110 | (S)-38 | pIC50 | = | 7 | ALA4423302 | 7.00 | nM | Homo sapiens | |||
| 13. | ALA4462110 | (S)-38 | INH | = | 102 | % | ALA4423301 | % | Rattus norvegicus | |||
| 14. | ALA4462110 | (S)-38 | pIC50 | = | 7.1 | ALA4423300 | 7.10 | nM | Rattus norvegicus | |||
| 15. | ALA4462110 | (S)-38 | pIC50 | 0 | ALA4423298 | Not Determined | Homo sapiens | |||||
| 16. | ALA4462110 | (S)-38 | CLH | = | 4.6 | uL/min | ALA4423297 | uL/min | ||||
| 17. | ALA4462110 | (S)-38 | pIC50 | = | 6 | ALA4423293 | 6.00 | nM | Homo sapiens | |||
| 18. | ALA4462110 | (S)-38 | pKi | = | 6.8 | ALA4423291 | 6.80 | nM | Homo sapiens | |||
| 19. | ALA4462110 | (S)-38 | pKi | = | 7 | ALA4423290 | 7.00 | nM | Homo sapiens | |||
| 20. | ALA4462110 | (S)-38 | logD | = | 1.8 | ALA4423288 |
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