# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4462192 | 15; TPN171 | Activity | 0 | ALA4397499 | Active | Rattus norvegicus | |||||
2. | ALA4462192 | 15; TPN171 | Activity | 0 | ALA4397498 | Active | Rattus norvegicus | |||||
3. | ALA4462192 | 15; TPN171 | Activity | 0 | ALA4397497 | Active | Rattus norvegicus | |||||
4. | ALA4462192 | 15; TPN171 | Activity | 0 | ALA4397495 | Active | Rattus norvegicus | |||||
5. | ALA4462192 | 15; TPN171 | Activity | 0 | ALA4397494 | Active | Rattus norvegicus | |||||
6. | ALA4462192 | 15; TPN171 | beta t1/2 | = | 10.9 | hr | ALA4397493 | hr | ||||
7. | ALA4462192 | 15; TPN171 | F | = | 67 | % | ALA4397481 | % | ||||
8. | ALA4462192 | 15; TPN171 | Vdss | = | 3.83 | L/Kg | ALA4397480 | L.kg-1 | ||||
9. | ALA4462192 | 15; TPN171 | CL | = | 0.648 | L/hr/kg | ALA4397479 | mL.min-1.kg-1 | ||||
10. | ALA4462192 | 15; TPN171 | t1/2 | = | 4.89 | hr | ALA4397478 | hr | ||||
11. | ALA4462192 | 15; TPN171 | t1/2 | = | 4.5 | hr | ALA4397477 | hr | ||||
12. | ALA4462192 | 15; TPN171 | MRT | = | 7.21 | hr | ALA4397476 | hr | ||||
13. | ALA4462192 | 15; TPN171 | MRT | = | 6.07 | hr | ALA4397475 | hr | ||||
14. | ALA4462192 | 15; TPN171 | AUC | = | 514 | ng/hr/ml | ALA4397474 | ng.hr.mL-1 | ||||
15. | ALA4462192 | 15; TPN171 | AUC | = | 773 | ng/hr/ml | ALA4397473 | ng.hr.mL-1 | ||||
16. | ALA4462192 | 15; TPN171 | AUCt | = | 495 | ng/hr/ml | ALA4397472 | ng.hr.mL-1 | ||||
17. | ALA4462192 | 15; TPN171 | AUCt | = | 752 | ng/hr/ml | ALA4397471 | ng.hr.mL-1 | ||||
18. | ALA4462192 | 15; TPN171 | Cmax | = | 66.5 | ng/ml | ALA4397470 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
19. | ALA4462192 | 15; TPN171 | Tmax | = | 1.9 | hr | ALA4397469 | hr | ||||
20. | ALA4462192 | 15; TPN171 | F | = | 66.4 | % | ALA4397468 | % |