# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4462270 | 35.HCl; AGH-192 | INH | = | 25 | % | ALA4394026 | % | Homo sapiens | |||
2. | ALA4462270 | 35.HCl; AGH-192 | INH | = | 6 | % | ALA4394041 | % | Homo sapiens | |||
3. | ALA4462270 | 35.HCl; AGH-192 | Drug uptake | 0 | ALA4394071 | Active | ||||||
4. | ALA4462270 | 35.HCl; AGH-192 | Drug uptake | 0 | ALA4394070 | Active | ||||||
5. | ALA4462270 | 35.HCl; AGH-192 | Drug uptake | 0 | ALA4394069 | Active | ||||||
6. | ALA4462270 | 35.HCl; AGH-192 | t1/2 | = | 202 | min | ALA4394061 | hr | ||||
7. | ALA4462270 | 35.HCl; AGH-192 | Ratio | = | 2 | ALA4394060 | Mus musculus | |||||
8. | ALA4462270 | 35.HCl; AGH-192 | t1/2 | = | 190 | min | ALA4394059 | hr | ||||
9. | ALA4462270 | 35.HCl; AGH-192 | Vdss | = | 2.8 | L/Kg | ALA4394058 | L.kg-1 | ||||
10. | ALA4462270 | 35.HCl; AGH-192 | Vd | = | 33.5 | L/Kg | ALA4394056 | L.kg-1 | ||||
11. | ALA4462270 | 35.HCl; AGH-192 | Cmax | = | 1069 | ng/g | ALA4394054 | ng/g | ||||
12. | ALA4462270 | 35.HCl; AGH-192 | Tmax | = | 30 | min | ALA4394050 | hr | ||||
13. | ALA4462270 | 35.HCl; AGH-192 | F | = | 24 | % | ALA4394053 | % | ||||
14. | ALA4462270 | 35.HCl; AGH-192 | F | = | 39 | % | ALA4394052 | % | ||||
15. | ALA4462270 | 35.HCl; AGH-192 | Ratio | = | 1.88 | ALA4394024 | ||||||
16. | ALA4462270 | 35.HCl; AGH-192 | Kp | = | 3.48 | ALA4394025 | Mus musculus | |||||
17. | ALA4462270 | 35.HCl; AGH-192 | Tmax | = | 5 | min | ALA4394072 | hr | ||||
18. | ALA4462270 | 35.HCl; AGH-192 | INH | = | 1 | % | ALA4394040 | % | Homo sapiens | |||
19. | ALA4462270 | 35.HCl; AGH-192 | INH | = | 0 | % | ALA4394039 | % | Homo sapiens | |||
20. | ALA4462270 | 35.HCl; AGH-192 | INH | = | -1 | % | ALA4394038 | % | Homo sapiens |