# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4463124 | 49 | AUC | = | 1165 | ng.hr/ml | ALA4398107 | ng.hr.mL-1 | ||||
2. | ALA4463124 | 49 | t1/2 | = | 24.1 | hr | ALA4398108 | hr | ||||
3. | ALA4463124 | 49 | Tmax | = | 8 | hr | ALA4398109 | hr | ||||
4. | ALA4463124 | 49 | Cmax | = | 75.4 | ng/ml | ALA4398110 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA4463124 | 49 | AUClast | = | 1412 | ng.hr/ml | ALA4398111 | ng.hr.mL-1 | ||||
6. | ALA4463124 | 49 | AUC | = | 3032 | ng.hr/ml | ALA4398112 | ng.hr.mL-1 | ||||
7. | ALA4463124 | 49 | F | = | 48.8 | % | ALA4398113 | % | ||||
8. | ALA4463124 | 49 | Cp | = | 120 | nM | ALA4398114 | nM | ||||
9. | ALA4463124 | 49 | PPB | = | 98 | % | ALA4398115 | % | ||||
10. | ALA4463124 | 49 | TGI | = | 53.5 | % | ALA4398116 | % | Homo sapiens | |||
11. | ALA4463124 | 49 | INH | 0 | ALA4398117 | Active | % | Mus musculus | ||||
12. | ALA4463124 | 49 | INH | 0 | ALA4398118 | Active | % | Mus musculus | ||||
13. | ALA4463124 | 49 | INH | 0 | ALA4398119 | Active | % | Mus musculus | ||||
14. | ALA4463124 | 49 | Drug uptake | = | 80724 | ng/g | ALA4398120 | ng/g | ||||
15. | ALA4463124 | 49 | Ratio | = | 20 | ALA4398121 | ||||||
16. | ALA4463124 | 49 | Activity | 0 | ALA4398128 | Non-Toxic | ||||||
17. | ALA4463124 | 49 | Activity | 0 | ALA4398129 | Non-Toxic | ||||||
18. | ALA4463124 | 49 | Ratio IC50 | = | 380 | ALA4398067 | ||||||
19. | ALA4463124 | 49 | IC50 | > | 10 | uM | ALA4398069 | nM | Homo sapiens | |||
20. | ALA4463124 | 49 | IC50 | = | 3.7 | uM | ALA4398070 | 5.43 | nM | Homo sapiens |