| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4463138 | 15 | IC50 | > | 10 | uM | ALA4417040 | nM | Homo sapiens | |||
| 2. | ALA4463138 | 15 | Drug recovery | < | 1 | % | ALA4417036 | % | ||||
| 3. | ALA4463138 | 15 | t1/2 | = | 2.65 | hr | ALA4417057 | hr | ||||
| 4. | ALA4463138 | 15 | Vdss | = | 0.4 | L/Kg | ALA4417056 | L.kg-1 | ||||
| 5. | ALA4463138 | 15 | CL | = | 0.27 | L/hr/kg | ALA4417055 | mL.min-1.kg-1 | ||||
| 6. | ALA4463138 | 15 | Ratio | = | 0.08 | ALA4417054 | ||||||
| 7. | ALA4463138 | 15 | AUC | = | 10 | ng/mL.hr | ALA4417053 | ng.hr.mL-1 | ||||
| 8. | ALA4463138 | 15 | Fu | = | 1.1 | % | ALA4417052 | |||||
| 9. | ALA4463138 | 15 | Fu | = | 1.1 | % | ALA4417051 | |||||
| 10. | ALA4463138 | 15 | Ratio | = | 0.9 | ALA4417050 | ||||||
| 11. | ALA4463138 | 15 | permeability | = | 21 | 10'-6 cm/s | ALA4417049 | 10'-6 cm/s | ||||
| 12. | ALA4463138 | 15 | solubility | = | 13 | ug ml-1 | ALA4417048 | ug.mL-1 | ||||
| 13. | ALA4463138 | 15 | IC50 | = | 12 | nM | ALA4417039 | 7.92 | nM | Homo sapiens | ||
| 14. | ALA4463138 | 15 | IC50 | = | 59 | nM | ALA4417038 | 7.23 | nM | Homo sapiens |
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