# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4463242 | 10d | BPR | = | 0.12 | ALA4430331 | ||||||
2. | ALA4463242 | 10d | Tmax | = | 26 | min | ALA4430330 | hr | ||||
3. | ALA4463242 | 10d | Cmax | = | 0.28 | ug ml-1 | ALA4430329 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
4. | ALA4463242 | 10d | beta t1/2 | = | 65.14 | min | ALA4430328 | hr | ||||
5. | ALA4463242 | 10d | AUClast | = | 16.38 | microg.min/mL | ALA4430327 | ng.hr.mL-1 | ||||
6. | ALA4463242 | 10d | AUC | = | 17.62 | microg.min/mL | ALA4430326 | ng.hr.mL-1 | ||||
7. | ALA4463242 | 10d | F | = | 7.6 | % | ALA4430325 | % | ||||
8. | ALA4463242 | 10d | BPR | = | 0.29 | ALA4430324 | ||||||
9. | ALA4463242 | 10d | MRT | = | 18.2 | min | ALA4430323 | hr | ||||
10. | ALA4463242 | 10d | CL | = | 43.77 | ml/min.kg | ALA4430322 | mL.min-1.kg-1 | ||||
11. | ALA4463242 | 10d | beta t1/2 | = | 19.9 | min | ALA4430321 | hr | ||||
12. | ALA4463242 | 10d | AUClast | = | 231.23 | microg.min/mL | ALA4430320 | ng.hr.mL-1 | ||||
13. | ALA4463242 | 10d | AUC | = | 231.3 | microg.min/mL | ALA4430319 | ng.hr.mL-1 | ||||
14. | ALA4463242 | 10d | FC | = | 2 | ALA4430318 | Rattus norvegicus | |||||
15. | ALA4463242 | 10d | Activity | 0 | ALA4430317 | Not Active | Rattus norvegicus | |||||
16. | ALA4463242 | 10d | Stability | = | 78.5 | % | ALA4430316 | % | ||||
17. | ALA4463242 | 10d | Activity | = | 74.6 | % | ALA4430315 | % | Homo sapiens | |||
18. | ALA4463242 | 10d | Activity | = | 60.8 | % | ALA4430314 | % | Homo sapiens | |||
19. | ALA4463242 | 10d | Activity | = | 64.6 | % | ALA4430313 | % | Homo sapiens | |||
20. | ALA4463242 | 10d | Activity | = | 94 | % | ALA4430312 | % | Homo sapiens |