# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4463697 | 13; VNRX-5133 | IC50 | = | 2500 | nM | ALA5232741 | 5.60 | nM | |||
2. | ALA4463697 | 13; VNRX-5133 | IC50 | = | 0.5 | nM | ALA5232740 | 9.30 | nM | |||
3. | ALA4463697 | 13; VNRX-5133 | IC50 | = | 7.9 | nM | ALA5232739 | 8.10 | nM | Escherichia coli | ||
4. | ALA4463697 | 13; VNRX-5133 | IC50 | = | 10 | nM | ALA5232738 | 8.00 | nM | |||
5. | ALA4463697 | 13; VNRX-5133 | MIC | <= | 0.125 | ug ml-1 | ALA4699873 | ug.mL-1 | Klebsiella pneumoniae | |||
6. | ALA4463697 | 13; VNRX-5133 | MIC | <= | 0.125 | ug ml-1 | ALA4699872 | ug.mL-1 | Klebsiella pneumoniae | |||
7. | ALA4463697 | 13; VNRX-5133 | t1/2 | = | 34000000 | min | ALA4699871 | hr | ||||
8. | ALA4463697 | 13; VNRX-5133 | K | = | 0.003 | 10^-8/s | ALA4699870 | 10^-8/s | ||||
9. | ALA4463697 | 13; VNRX-5133 | K | = | 1 | 10^4/M/s | ALA4699869 | 10^4/M/s | ||||
10. | ALA4463697 | 13; VNRX-5133 | Ki(app) | = | 1.3 | uM | ALA4699868 | 5.89 | nM | |||
11. | ALA4463697 | 13; VNRX-5133 | IC50 | = | 37 | nM | ALA4699867 | 7.43 | nM | |||
12. | ALA4463697 | 13; VNRX-5133 | IC50 | = | 0.01 | uM | ALA4623096 | 8.00 | nM | |||
13. | ALA4463697 | 13; VNRX-5133 | Activity | = | 4.87 | log10CFU | ALA4357098 | log10CFU | Escherichia coli | |||
14. | ALA4463697 | 13; VNRX-5133 | Activity | = | 4.51 | log10CFU | ALA4357097 | log10CFU | Klebsiella pneumoniae | |||
15. | ALA4463697 | 13; VNRX-5133 | INH | 0 | ALA4357092 | Not Active | % | Homo sapiens | ||||
16. | ALA4463697 | 13; VNRX-5133 | INH | 0 | ALA4357091 | Not Active | % | Homo sapiens | ||||
17. | ALA4463697 | 13; VNRX-5133 | INH | 0 | ALA4357090 | Not Active | % | Homo sapiens | ||||
18. | ALA4463697 | 13; VNRX-5133 | INH | 0 | ALA4357089 | Not Active | % | Homo sapiens | ||||
19. | ALA4463697 | 13; VNRX-5133 | INH | 0 | ALA4357088 | Not Active | % | Homo sapiens | ||||
20. | ALA4463697 | 13; VNRX-5133 | INH | 0 | ALA4357087 | Not Active | % | Homo sapiens |