| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4463882 | 22d | Papp | = | 51 | 10'-6 cm/s | ALA4403255 | 10'-6 cm/s | ||||
| 2. | ALA4463882 | 22d | Papp | = | 23 | 10'-6 cm/s | ALA4403254 | 10'-6 cm/s | ||||
| 3. | ALA4463882 | 22d | F | = | 68 | % | ALA4403249 | % | ||||
| 4. | ALA4463882 | 22d | t1/2 | = | 1 | hr | ALA4403248 | hr | ||||
| 5. | ALA4463882 | 22d | AUC | = | 20.98 | uM.hr | ALA4403247 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 6. | ALA4463882 | 22d | Cmax | = | 27.22 | uM | ALA4403246 | nM | ||||
| 7. | ALA4463882 | 22d | Stability | = | 97 | % | ALA4403244 | % | ||||
| 8. | ALA4463882 | 22d | IC50 | = | 29 | uM | ALA4403243 | 4.54 | nM | Homo sapiens | ||
| 9. | ALA4463882 | 22d | IC50 | = | 74.3 | uM | ALA4403242 | 4.13 | nM | Homo sapiens | ||
| 10. | ALA4463882 | 22d | IC50 | > | 100 | uM | ALA4403241 | nM | Sus scrofa | |||
| 11. | ALA4463882 | 22d | IC50 | > | 100 | uM | ALA4403240 | nM | Homo sapiens | |||
| 12. | ALA4463882 | 22d | IC50 | > | 100 | uM | ALA4403239 | nM | Homo sapiens | |||
| 13. | ALA4463882 | 22d | IC50 | = | 24.24 | uM | ALA4403237 | 4.62 | nM | Homo sapiens | ||
| 14. | ALA4463882 | 22d | IC50 | > | 100 | uM | ALA4403236 | nM | ||||
| 15. | ALA4463882 | 22d | Ratio IC50 | <= | 7 | ALA4403234 | Homo sapiens | |||||
| 16. | ALA4463882 | 22d | IC50 | = | 0.176 | uM | ALA4403233 | 6.75 | nM | Homo sapiens | ||
| 17. | ALA4463882 | 22d | IC50 | = | 0.425 | uM | ALA4403232 | 6.37 | nM | Homo sapiens | ||
| 18. | ALA4463882 | 22d | IC50 | = | 1.238 | uM | ALA4403231 | 5.91 | nM | Homo sapiens |
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