# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4464582 | 11 | AUCt | = | 6979 | ng/ml/hr | ALA4388513 | ng.hr.mL-1 | ||||
2. | ALA4464582 | 11 | Cmax | = | 508.42 | mg/L | ALA4388512 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
3. | ALA4464582 | 11 | Tmax | = | 6 | hr | ALA4388511 | hr | ||||
4. | ALA4464582 | 11 | F | = | 60 | % | ALA4388510 | % | ||||
5. | ALA4464582 | 11 | TGI | = | 77 | % | ALA4388509 | % | Homo sapiens | |||
6. | ALA4464582 | 11 | TGI | = | 53 | % | ALA4388508 | % | Homo sapiens | |||
7. | ALA4464582 | 11 | Activity | 0 | ALA4388507 | Non-Toxic | ||||||
8. | ALA4464582 | 11 | TGI | 0 | ALA4388506 | Dose-dependent effect | Homo sapiens | |||||
9. | ALA4464582 | 11 | IC50 | = | 36.81 | nM | ALA4388505 | 7.43 | nM | Homo sapiens | ||
10. | ALA4464582 | 11 | IC50 | = | 18.72 | nM | ALA4388504 | 7.73 | nM | Homo sapiens | ||
11. | ALA4464582 | 11 | IC50 | = | 71 | nM | ALA4388503 | 7.15 | nM | Homo sapiens | ||
12. | ALA4464582 | 11 | IC50 | = | 4 | nM | ALA4388502 | 8.40 | nM | Homo sapiens | ||
13. | ALA4464582 | 11 | IC50 | = | 41.3 | nM | ALA4388501 | 7.38 | nM | Homo sapiens |