| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4464849 | 4az | AUC | = | 331 | micromol.hr/L | ALA4375456 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 2. | ALA4464849 | 4az | AUC | = | 130 | micromol.hr/L | ALA4375455 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 3. | ALA4464849 | 4az | Activity | > | 50 | % | ALA4375454 | % | Mus musculus | |||
| 4. | ALA4464849 | 4az | Activity | 0 | ALA4375453 | Non-Toxic | ||||||
| 5. | ALA4464849 | 4az | Activity | 0 | ALA4375452 | Non-Toxic | ||||||
| 6. | ALA4464849 | 4az | Activity | 0 | ALA4375438 | Non-Toxic | ||||||
| 7. | ALA4464849 | 4az | Activity | 0 | ALA4375451 | Active | Mus musculus | |||||
| 8. | ALA4464849 | 4az | Activity | 0 | ALA4375450 | Active | Mus musculus | |||||
| 9. | ALA4464849 | 4az | Activity | 0 | ALA4375449 | Active | Mus musculus | |||||
| 10. | ALA4464849 | 4az | F | = | 39 | % | ALA4375426 | % | ||||
| 11. | ALA4464849 | 4az | Tmax | = | 0.5 | hr | ALA4375428 | hr | ||||
| 12. | ALA4464849 | 4az | Tmax | = | 6.5 | hr | ALA4375427 | hr | ||||
| 13. | ALA4464849 | 4az | Cmax | = | 29.1 | uM | ALA4375429 | nM | ||||
| 14. | ALA4464849 | 4az | Cmax | = | 4.7 | uM | ALA4375431 | nM | ||||
| 15. | ALA4464849 | 4az | INH | 0 | ALA4375443 | Not Active | % | Homo sapiens | ||||
| 16. | ALA4464849 | 4az | INH | 0 | ALA4375442 | Not Active | % | Mus musculus | ||||
| 17. | ALA4464849 | 4az | IC50 | = | 0.04 | uM | ALA4375439 | 7.40 | nM | Mus musculus | ||
| 18. | ALA4464849 | 4az | INH | 0 | ALA4375441 | Not Active | % | Mus musculus | ||||
| 19. | ALA4464849 | 4az | IC50 | = | 0.035 | uM | ALA4375440 | 7.46 | nM | Mus musculus | ||
| 20. | ALA4464849 | 4az | Drug uptake | = | 1 | uM | ALA4375446 | uM |
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