# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4464946 | 16; M8891 | Activity | 0 | ALA4417072 | Non-Toxic | ||||||
2. | ALA4464946 | 16; M8891 | T/C | = | 22 | % | ALA4417071 | % | Homo sapiens | |||
3. | ALA4464946 | 16; M8891 | Activity | 0 | ALA4417070 | Non-Toxic | ||||||
4. | ALA4464946 | 16; M8891 | T/C | = | 19 | % | ALA4417069 | % | Homo sapiens | |||
5. | ALA4464946 | 16; M8891 | Ratio | = | 4 | ALA4417068 | ||||||
6. | ALA4464946 | 16; M8891 | Papp | = | 15 | 10'-6 cm/s | ALA4417067 | 10'-6 cm/s | ||||
7. | ALA4464946 | 16; M8891 | F | = | 80 | % | ALA4417076 | % | ||||
8. | ALA4464946 | 16; M8891 | F | = | 67 | % | ALA4417075 | % | ||||
9. | ALA4464946 | 16; M8891 | F | = | 65 | % | ALA4417074 | % | ||||
10. | ALA4464946 | 16; M8891 | F | = | 38 | % | ALA4417073 | % | ||||
11. | ALA4464946 | 16; M8891 | t1/2 | = | 4.7 | hr | ALA4417066 | hr | ||||
12. | ALA4464946 | 16; M8891 | t1/2 | = | 3.89 | hr | ALA4417065 | hr | ||||
13. | ALA4464946 | 16; M8891 | t1/2 | = | 3.36 | hr | ALA4417064 | hr | ||||
14. | ALA4464946 | 16; M8891 | t1/2 | = | 0.801 | hr | ALA4417063 | hr | ||||
15. | ALA4464946 | 16; M8891 | Vdss | = | 0.227 | L/Kg | ALA4417062 | L.kg-1 | ||||
16. | ALA4464946 | 16; M8891 | Vdss | = | 0.407 | L/Kg | ALA4417061 | L.kg-1 | ||||
17. | ALA4464946 | 16; M8891 | Vdss | = | 1.34 | L/Kg | ALA4417060 | L.kg-1 | ||||
18. | ALA4464946 | 16; M8891 | CL | = | 0.034 | L/hr/kg | ALA4417059 | mL.min-1.kg-1 | ||||
19. | ALA4464946 | 16; M8891 | CL | = | 0.078 | L/hr/kg | ALA4417037 | mL.min-1.kg-1 | ||||
20. | ALA4464946 | 16; M8891 | CL | = | 0.35 | L/hr/kg | ALA4417058 | mL.min-1.kg-1 |