| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4466696 | 32 | Ratio IC50 | < | 10 | ALA4433053 | ||||||
| 2. | ALA4466696 | 32 | Ratio IC50 | < | 10 | ALA4433077 | ||||||
| 3. | ALA4466696 | 32 | Ratio IC50 | < | 10 | ALA4433076 | ||||||
| 4. | ALA4466696 | 32 | pIC50 | = | 6.3 | ALA4433050 | 6.30 | nM | Homo sapiens | |||
| 5. | ALA4466696 | 32 | pIC50 | = | 6.6 | ALA4433048 | 6.60 | nM | Homo sapiens | |||
| 6. | ALA4466696 | 32 | Activity | 0 | ALA4433072 | Non-Toxic | ||||||
| 7. | ALA4466696 | 32 | pIC50 | = | 7 | ALA4433071 | 7.00 | nM | Homo sapiens | |||
| 8. | ALA4466696 | 32 | pIC50 | = | 6.6 | ALA4433070 | 6.60 | nM | Homo sapiens | |||
| 9. | ALA4466696 | 32 | Ratio IC50 | > | 100 | ALA4433069 | ||||||
| 10. | ALA4466696 | 32 | t1/2 | = | 1.7 | hr | ALA4433068 | hr | ||||
| 11. | ALA4466696 | 32 | Activity | 0 | ALA4433067 | Non-Toxic | ||||||
| 12. | ALA4466696 | 32 | pIC50 | < | 5 | ALA4433066 | nM | Homo sapiens | ||||
| 13. | ALA4466696 | 32 | INH | = | 85 | % | ALA4433065 | % | Rattus norvegicus | |||
| 14. | ALA4466696 | 32 | INH | = | 45 | % | ALA4433064 | % | Rattus norvegicus | |||
| 15. | ALA4466696 | 32 | INH | 0 | ALA4433063 | Dose-dependent effect | % | Rattus norvegicus | ||||
| 16. | ALA4466696 | 32 | pKa | = | 7.7 | ALA4433062 | ||||||
| 17. | ALA4466696 | 32 | AUC | = | 469 | hr.ng/ml | ALA4433061 | ng.hr.mL-1 | ||||
| 18. | ALA4466696 | 32 | Cmax | = | 96 | ng/ml | ALA4433060 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 19. | ALA4466696 | 32 | F | = | 55 | % | ALA4433059 | % | ||||
| 20. | ALA4466696 | 32 | CL | = | 54 | ml/min.kg | ALA4433057 | mL.min-1.kg-1 |
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