# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4468379 | 23 | t1/2 | = | 1.2 | hr | ALA4385731 | hr | ||||
2. | ALA4468379 | 23 | F | = | 29.2 | % | ALA4385730 | % | ||||
3. | ALA4468379 | 23 | AUCt | = | 2009 | hr.ng/ml | ALA4385729 | ng.hr.mL-1 | ||||
4. | ALA4468379 | 23 | Cmax | = | 643 | ng/ml | ALA4385728 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA4468379 | 23 | CL | = | 25.8 | ml/kg/min | ALA4385727 | mL.min-1.kg-1 | ||||
6. | ALA4468379 | 23 | Vdss | = | 0.853 | L/Kg | ALA4385726 | L.kg-1 | ||||
7. | ALA4468379 | 23 | AUCt | = | 1400 | hr.ng/ml | ALA4385725 | ng.hr.mL-1 | ||||
8. | ALA4468379 | 23 | t1/2 | = | 0.518 | hr | ALA4385724 | hr | ||||
9. | ALA4468379 | 23 | Ratio IC50 | = | 34 | ALA4385723 | ||||||
10. | ALA4468379 | 23 | Ratio IC50 | = | 167 | ALA4385722 | ||||||
11. | ALA4468379 | 23 | Ratio IC50 | = | 791 | ALA4385716 | ||||||
12. | ALA4468379 | 23 | IC50 | = | 156 | nM | ALA4385721 | 6.81 | nM | Homo sapiens | ||
13. | ALA4468379 | 23 | IC50 | = | 766 | nM | ALA4385717 | 6.12 | nM | Homo sapiens | ||
14. | ALA4468379 | 23 | IC50 | = | 3637 | nM | ALA4385720 | 5.44 | nM | Homo sapiens | ||
15. | ALA4468379 | 23 | GI50 | = | 33.2 | nM | ALA4385719 | nM | Homo sapiens | |||
16. | ALA4468379 | 23 | IC50 | = | 4.6 | nM | ALA4385718 | 8.34 | nM | Homo sapiens | ||
17. | ALA4468379 | 23 | IC50 | = | 6 | nM | ALA4351130 | 8.22 | nM | Homo sapiens | ||
18. | ALA4468379 | 23 | Ratio IC50 | = | 170 | ALA4351129 | ||||||
19. | ALA4468379 | 23 | Ratio IC50 | = | 790 | ALA4351128 | ||||||
20. | ALA4468379 | 23 | IC50 | = | 34 | nM | ALA4351127 | 7.47 | nM | Homo sapiens |