Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4470291	6a; AM-0687	fIC50	=	2882	nM	ALA4428735			nM	Homo sapiens
2.	ALA4470291	6a; AM-0687	fIC50	=	0.61	nM	ALA4428713			nM	Mus musculus
3.	ALA4470291	6a; AM-0687	INH		0		ALA4428734		Dose-dependent effect	%	Rattus norvegicus
4.	ALA4470291	6a; AM-0687	INH		0		ALA4428733		Dose-dependent effect	%	Rattus norvegicus
5.	ALA4470291	6a; AM-0687	INH		0		ALA4428732		Dose-dependent effect	%	Mus musculus
6.	ALA4470291	6a; AM-0687	INH		0		ALA4428731		Dose-dependent effect	%	Mus musculus
7.	ALA4470291	6a; AM-0687	fIC50	=	4.6	nM	ALA4428725			nM	Homo sapiens
8.	ALA4470291	6a; AM-0687	Activity		0		ALA4428737		Non-Toxic
9.	ALA4470291	6a; AM-0687	Fu	=	0.876		ALA4428736
10.	ALA4470291	6a; AM-0687	IC50	=	3290	nM	ALA4428735	5.48		nM	Homo sapiens
11.	ALA4470291	6a; AM-0687	ED50	=	0.016	mg kg-1	ALA4428734			mg.kg-1	Rattus norvegicus
12.	ALA4470291	6a; AM-0687	ED50	=	0.026	mg kg-1	ALA4428733			mg.kg-1	Rattus norvegicus
13.	ALA4470291	6a; AM-0687	ED50	=	0.04	mg kg-1	ALA4428732			mg.kg-1	Mus musculus
14.	ALA4470291	6a; AM-0687	ED50	<	0.01	mg kg-1	ALA4428731			mg.kg-1	Mus musculus
15.	ALA4470291	6a; AM-0687	F	=	70	%	ALA4428730			%
16.	ALA4470291	6a; AM-0687	Fu	=	0.22		ALA4428729
17.	ALA4470291	6a; AM-0687	Fu	=	0.11		ALA4428728
18.	ALA4470291	6a; AM-0687	Papp	=	14.6	ucm/s	ALA4428727			ucm/s
19.	ALA4470291	6a; AM-0687	solubility	=	200	ug ml-1	ALA4428726			ug.mL-1
20.	ALA4470291	6a; AM-0687	IC50	=	42	nM	ALA4428725	7.38		nM	Homo sapiens