| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4470529 | 15 | F | = | 100 | % | ALA4348519 | % | ||||
| 2. | ALA4470529 | 15 | Vd | = | 9.93 | L/Kg | ALA4348518 | L.kg-1 | ||||
| 3. | ALA4470529 | 15 | CL | = | 36.7 | ml/min.kg | ALA4348517 | mL.min-1.kg-1 | ||||
| 4. | ALA4470529 | 15 | AUC | = | 1965.3 | ng.hr/ml | ALA4348516 | ng.hr.mL-1 | ||||
| 5. | ALA4470529 | 15 | AUCt | = | 1694.1 | ng.hr/ml | ALA4348515 | ng.hr.mL-1 | ||||
| 6. | ALA4470529 | 15 | t1/2 | = | 6.9 | hr | ALA4348514 | hr | ||||
| 7. | ALA4470529 | 15 | Cmax | = | 252.1 | ng/ml | ALA4348513 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 8. | ALA4470529 | 15 | F | = | 23 | % | ALA4348512 | % | ||||
| 9. | ALA4470529 | 15 | AUC | = | 4513.5 | ng.hr/ml | ALA4348511 | ng.hr.mL-1 | ||||
| 10. | ALA4470529 | 15 | AUCt | = | 3417.3 | ng.hr/ml | ALA4348481 | ng.hr.mL-1 | ||||
| 11. | ALA4470529 | 15 | t1/2 | = | 7.4 | hr | ALA4348510 | hr | ||||
| 12. | ALA4470529 | 15 | Cmax | = | 297.3 | ng/ml | ALA4348509 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | ALA4470529 | 15 | Tmax | = | 5.3 | hr | ALA4348508 | hr | ||||
| 14. | ALA4470529 | 15 | INH | 0 | ALA4348507 | Active | % | Homo sapiens | ||||
| 15. | ALA4470529 | 15 | INH | 0 | ALA4348506 | Active | % | Homo sapiens | ||||
| 16. | ALA4470529 | 15 | INH | 0 | ALA4348505 | Dose-dependent effect | % | Homo sapiens | ||||
| 17. | ALA4470529 | 15 | Ratio IC50 | = | 91 | ALA4348504 | ||||||
| 18. | ALA4470529 | 15 | Ratio IC50 | = | 477 | ALA4348503 | ||||||
| 19. | ALA4470529 | 15 | Ratio IC50 | = | 348 | ALA4348502 | ||||||
| 20. | ALA4470529 | 15 | Ratio IC50 | = | 178 | ALA4348501 |
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