# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4470693 | 13g | F | = | 11 | % | ALA4430384 | % | ||||
2. | ALA4470693 | 13g | AUC | = | 0.13 | microg.hr/mL | ALA4430383 | ng.hr.mL-1 | ||||
3. | ALA4470693 | 13g | AUC | = | 0.22 | microg.hr/mL | ALA4430382 | ng.hr.mL-1 | ||||
4. | ALA4470693 | 13g | t1/2 | = | 1.4 | hr | ALA4430381 | hr | ||||
5. | ALA4470693 | 13g | CL | = | 4.6 | L/hr/kg | ALA4430380 | mL.min-1.kg-1 | ||||
6. | ALA4470693 | 13g | AUC | = | 0.27 | microg.hr/mL | ALA4430379 | ng.hr.mL-1 | ||||
7. | ALA4470693 | 13g | Cmax | = | 0.25 | ug ml-1 | ALA4430378 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA4470693 | 13g | t1/2 | > | 60 | min | ALA4430377 | hr | ||||
9. | ALA4470693 | 13g | t1/2 | = | 28 | min | ALA4430376 | hr | ||||
10. | ALA4470693 | 13g | INH | = | 11 | % | ALA4430375 | % | Homo sapiens | |||
11. | ALA4470693 | 13g | INH | = | 28 | % | ALA4430374 | % | Homo sapiens | |||
12. | ALA4470693 | 13g | INH | = | 41 | % | ALA4430373 | % | Homo sapiens | |||
13. | ALA4470693 | 13g | logD | = | 4 | ALA4430372 | ||||||
14. | ALA4470693 | 13g | GI50 | = | 3 | uM | ALA4430371 | nM | Homo sapiens | |||
15. | ALA4470693 | 13g | GI50 | = | 1.7 | uM | ALA4430370 | nM | Homo sapiens | |||
16. | ALA4470693 | 13g | IC50 | = | 0.007 | uM | ALA4430369 | 8.15 | nM | Homo sapiens | ||
17. | ALA4470693 | 13g | IC50 | > | 1 | uM | ALA4430368 | nM | Homo sapiens | |||
18. | ALA4470693 | 13g | IC50 | 0 | ALA4430367 | Not Determined | Homo sapiens | |||||
19. | ALA4470693 | 13g | GI50 | = | 0.068 | uM | ALA4430366 | nM | Homo sapiens | |||
20. | ALA4470693 | 13g | IC50 | = | 0.077 | uM | ALA4430365 | 7.11 | nM | Homo sapiens |