# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4472492 | 18 | EC50 | = | 380 | nM | ALA4428531 | 6.42 | nM | |||
2. | ALA4472492 | 18 | Peff | = | 14.52 | ucm/s | ALA4428542 | ucm/s | ||||
3. | ALA4472492 | 18 | Peff | = | 19.18 | ucm/s | ALA4428541 | ucm/s | ||||
4. | ALA4472492 | 18 | Kinetic_solubility | > | 310 | ug ml-1 | ALA4428540 | ug.mL-1 | ||||
5. | ALA4472492 | 18 | Ratio IC50/EC50 | = | 420 | ALA4428539 | ||||||
6. | ALA4472492 | 18 | Ratio IC50/EC50 | > | 588 | ALA4428538 | ||||||
7. | ALA4472492 | 18 | IC50 | = | 71470 | nM | ALA4428537 | 4.15 | nM | |||
8. | ALA4472492 | 18 | IC50 | > | 100 | uM | ALA4428536 | nM | Mus musculus | |||
9. | ALA4472492 | 18 | IC50 | = | 77.76 | uM | ALA4428535 | 4.11 | nM | Mus musculus | ||
10. | ALA4472492 | 18 | IC50 | = | 83.68 | uM | ALA4428534 | 4.08 | nM | Mus musculus | ||
11. | ALA4472492 | 18 | IC50 | = | 74.12 | uM | ALA4428533 | 4.13 | nM | Mus musculus | ||
12. | ALA4472492 | 18 | Ratio EC50 | = | 2 | ALA4428532 | ||||||
13. | ALA4472492 | 18 | INH | 0 | ALA4428531 | Dose-dependent effect | % | |||||
14. | ALA4472492 | 18 | EC50 | = | 170 | nM | ALA4428530 | 6.77 | nM | |||
15. | ALA4472492 | 18 | Activity | 0 | ALA4428529 | Not Active | Plasmodium falciparum | |||||
16. | ALA4472492 | 18 | Ratio IC50 | = | 3.9 | ALA4428527 | ||||||
17. | ALA4472492 | 18 | Ratio IC50 | = | 6.4 | ALA4428528 | ||||||
18. | ALA4472492 | 18 | Activity | 0 | ALA4428526 | Not Active | Plasmodium falciparum | |||||
19. | ALA4472492 | 18 | Activity | 0 | ALA4428525 | Not Active | Plasmodium falciparum | |||||
20. | ALA4472492 | 18 | Activity | 0 | ALA4428524 | Not Active | Plasmodium falciparum |