| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4473252 | 17 | BPR | = | 1.53 | ALA4355774 | ||||||
| 2. | ALA4473252 | 17 | BPR | = | 0.9 | ALA4355773 | ||||||
| 3. | ALA4473252 | 17 | Drug uptake | = | 0.038 | nmol/g | ALA4355772 | nmol/g | ||||
| 4. | ALA4473252 | 17 | Drug uptake | = | 0.222 | nmol/g | ALA4355771 | nmol/g | ||||
| 5. | ALA4473252 | 17 | FC | = | 1.77 | ALA4355770 | Rattus norvegicus | |||||
| 6. | ALA4473252 | 17 | FC | = | 2.33 | ALA4355769 | Rattus norvegicus | |||||
| 7. | ALA4473252 | 17 | F | = | 75.3 | % | ALA4355768 | % | ||||
| 8. | ALA4473252 | 17 | Vdss | = | 10.5 | L/Kg | ALA4355765 | L.kg-1 | ||||
| 9. | ALA4473252 | 17 | CL | = | 43.7 | ml/min.kg | ALA4355760 | mL.min-1.kg-1 | ||||
| 10. | ALA4473252 | 17 | AUC/dose | = | 0.954 | uM.hr.kg/mg | ALA4355759 | uM.hr.kg/mg | ||||
| 11. | ALA4473252 | 17 | Fu | > | 99 | % | ALA4355757 | |||||
| 12. | ALA4473252 | 17 | EC50 | = | 177 | nM | ALA4355755 | 6.75 | nM | Rattus norvegicus | ||
| 13. | ALA4473252 | 17 | Ki | = | 9 | nM | ALA4355754 | 8.05 | nM | Homo sapiens | ||
| 14. | ALA4473252 | 17 | Fu | > | 99 | % | ALA4355753 | |||||
| 15. | ALA4473252 | 17 | Papp | = | 6.8 | 10'-6 cm/s | ALA4355751 | 10'-6 cm/s | ||||
| 16. | ALA4473252 | 17 | Ki | = | 1600 | nM | ALA4355756 | 5.80 | nM | Homo sapiens |
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