| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4473654 | 15 | CL | = | 39.1 | ml/min.kg | ALA4739570 | mL.min-1.kg-1 | ||||
| 2. | ALA4473654 | 15 | CL | = | 5.6 | ml/min.kg | ALA4739569 | mL.min-1.kg-1 | ||||
| 3. | ALA4473654 | 15 | Drugexcretion | = | 12.5 | % | ALA4739568 | % | ||||
| 4. | ALA4473654 | 15 | Vdss | = | 8.9 | L/Kg | ALA4739567 | L.kg-1 | ||||
| 5. | ALA4473654 | 15 | CL | = | 44.7 | ml/min.kg | ALA4739566 | mL.min-1.kg-1 | ||||
| 6. | ALA4473654 | 15 | Ratio | = | 2 | ALA4739565 | ||||||
| 7. | ALA4473654 | 15 | AUC | = | 1.6 | uM.hr | ALA4739564 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 8. | ALA4473654 | 15 | Vdss | = | 17.5 | L/Kg | ALA4739563 | L.kg-1 | ||||
| 9. | ALA4473654 | 15 | CL | = | 87.7 | ml/min.kg | ALA4739562 | mL.min-1.kg-1 | ||||
| 10. | ALA4473654 | 15 | t1/2 | = | 4.9 | hr | ALA4739561 | hr | ||||
| 11. | ALA4473654 | 15 | F | < | 5 | % | ALA4739519 | % | ||||
| 12. | ALA4473654 | 15 | Vdss | = | 2.2 | L/Kg | ALA4739511 | L.kg-1 | ||||
| 13. | ALA4473654 | 15 | CL | = | 60 | ml/min.kg | ALA4739510 | mL.min-1.kg-1 | ||||
| 14. | ALA4473654 | 15 | Ratio | = | 1.9 | ALA4739509 | ||||||
| 15. | ALA4473654 | 15 | AUC | = | 1.6 | uM.hr | ALA4739508 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 16. | ALA4473654 | 15 | Vdss | = | 4.1 | L/Kg | ALA4739507 | L.kg-1 | ||||
| 17. | ALA4473654 | 15 | CL | = | 114 | ml/min.kg | ALA4739506 | mL.min-1.kg-1 | ||||
| 18. | ALA4473654 | 15 | t1/2(app) | = | 0.73 | hr | ALA4739505 | hr | ||||
| 19. | ALA4473654 | 15 | IC50 | = | 22 | uM | ALA4739476 | 4.66 | nM | |||
| 20. | ALA4473654 | 15 | IC50 | = | 22 | uM | ALA4739475 | 4.66 | nM | Homo sapiens |
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