# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4474232 | 13f | MED | = | 12.5 | mg kg-1 | ALA4366718 | mg kg-1 | Homo sapiens | |||
2. | ALA4474232 | 13f | TGI | = | 95 | % | ALA4366724 | % | Homo sapiens | |||
3. | ALA4474232 | 13f | TGI | = | 50 | % | ALA4366723 | % | Homo sapiens | |||
4. | ALA4474232 | 13f | TGI | = | 114 | % | ALA4366721 | % | Homo sapiens | |||
5. | ALA4474232 | 13f | TGI | = | 100 | % | ALA4366720 | % | Homo sapiens | |||
6. | ALA4474232 | 13f | TGI | = | 53 | % | ALA4366719 | % | Homo sapiens | |||
7. | ALA4474232 | 13f | INH | 0 | ALA4366718 | Dose-dependent effect | % | Homo sapiens | ||||
8. | ALA4474232 | 13f | Fu | < | 0.5 | % | ALA4366717 | |||||
9. | ALA4474232 | 13f | Fu | < | 0.5 | % | ALA4366716 | |||||
10. | ALA4474232 | 13f | Fu | < | 0.5 | % | ALA4366715 | |||||
11. | ALA4474232 | 13f | Vd | = | 3.6 | L/Kg | ALA4366714 | L.kg-1 | ||||
12. | ALA4474232 | 13f | CL | = | 0.8 | L/hr/kg | ALA4366713 | mL.min-1.kg-1 | ||||
13. | ALA4474232 | 13f | AUC | = | 3.1 | microg.hr/mL | ALA4366712 | ng.hr.mL-1 | ||||
14. | ALA4474232 | 13f | t1/2 | = | 3.2 | hr | ALA4366711 | hr | ||||
15. | ALA4474232 | 13f | F | = | 54 | % | ALA4366710 | % | ||||
16. | ALA4474232 | 13f | AUC | = | 6.7 | microg.hr/mL | ALA4366709 | ng.hr.mL-1 | ||||
17. | ALA4474232 | 13f | t1/2 | = | 5.1 | hr | ALA4366708 | hr | ||||
18. | ALA4474232 | 13f | Tmax | = | 1.2 | hr | ALA4366707 | hr | ||||
19. | ALA4474232 | 13f | Cmax | = | 1.6 | ug ml-1 | ALA4366706 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
20. | ALA4474232 | 13f | INH | = | 100 | % | ALA4366705 | % | Homo sapiens |