| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4474353 | 12 | Drug metabolism | 0 | ALA4333223 | Metabolite_Detected | ||||||
| 2. | ALA4474353 | 12 | Drug metabolism | 0 | ALA4333222 | Metabolite_Detected | ||||||
| 3. | ALA4474353 | 12 | INH | 0 | ALA4333221 | Active | % | Mus musculus | ||||
| 4. | ALA4474353 | 12 | INH | 0 | ALA4333220 | Active | % | Mus musculus | ||||
| 5. | ALA4474353 | 12 | INH | 0 | ALA4333219 | Active | % | Mus musculus | ||||
| 6. | ALA4474353 | 12 | INH | 0 | ALA4333218 | Dose-dependent effect | % | Mus musculus | ||||
| 7. | ALA4474353 | 12 | pIC50 | = | 5.5 | ALA4333217 | 5.50 | nM | Homo sapiens | |||
| 8. | ALA4474353 | 12 | Activity | 0 | ALA4333216 | Dose-dependent effect | ||||||
| 9. | ALA4474353 | 12 | pEC50 | = | 5.78 | ALA4333216 | 5.78 | nM | ||||
| 10. | ALA4474353 | 12 | Papp | = | 7.67 | 10'-6 cm/s | ALA4333215 | 10'-6 cm/s | ||||
| 11. | ALA4474353 | 12 | Papp | = | 12.5 | 10'-6 cm/s | ALA4333214 | 10'-6 cm/s | ||||
| 12. | ALA4474353 | 12 | Stability | 0 | ALA4333213 | Stable | % | |||||
| 13. | ALA4474353 | 12 | Stability | 0 | ALA4333212 | Stable | % | |||||
| 14. | ALA4474353 | 12 | solubility | = | 8 | mg/ml | ALA4333211 | ug.mL-1 | ||||
| 15. | ALA4474353 | 12 | logD | = | 2.14 | ALA4333210 | ||||||
| 16. | ALA4474353 | 12 | Kinetic_solubility | >= | 394 | uM | ALA4333209 | nM | ||||
| 17. | ALA4474353 | 12 | Activity | 0 | ALA4333208 | Active | Homo sapiens | |||||
| 18. | ALA4474353 | 12 | Activity | 0 | ALA4333207 | Active | Homo sapiens | |||||
| 19. | ALA4474353 | 12 | FC | = | 24.9 | ALA4333206 | ||||||
| 20. | ALA4474353 | 12 | pIC50 | < | 4 | ALA4333205 | nM | Homo sapiens |
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