# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4474636 | 20 | F | 0 | ALA4359959 | Bld | % | |||||
2. | ALA4474636 | 20 | AUC | 0 | ALA4359955 | Bld | ||||||
3. | ALA4474636 | 20 | Cmax | 0 | ALA4359951 | Bld | ||||||
4. | ALA4474636 | 20 | Vdss | = | 0.4 | L/Kg | ALA4359950 | L.kg-1 | ||||
5. | ALA4474636 | 20 | CL | = | 18 | ml/min.kg | ALA4359949 | mL.min-1.kg-1 | ||||
6. | ALA4474636 | 20 | PPB | = | 99 | % | ALA4359948 | % | ||||
7. | ALA4474636 | 20 | PPB | = | 98 | % | ALA4359947 | % | ||||
8. | ALA4474636 | 20 | Papp | = | 8.4 | 10'-6 cm/s | ALA4359946 | 10'-6 cm/s | ||||
9. | ALA4474636 | 20 | IC50 | = | 8 | nM | ALA4359943 | 8.10 | nM | Homo sapiens | ||
10. | ALA4474636 | 20 | Ki | = | 24 | nM | ALA4359941 | 7.62 | nM | Homo sapiens | ||
11. | ALA4474636 | 20 | Ki | = | 0.5 | nM | ALA4359940 | 9.30 | nM | Homo sapiens |