Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4474912	61	INH		0		ALA4324040		Active	%	Homo sapiens
2.	ALA4474912	61	INH		0		ALA4324039		Active	%	Homo sapiens
3.	ALA4474912	61	Drug metabolism		0		ALA4324063		Metabolite_Detected
4.	ALA4474912	61	Stability		0		ALA4324061		Stable	%
5.	ALA4474912	61	Drug metabolism		0		ALA4324060		Metabolite_Notdetected
6.	ALA4474912	61	t1/2lambda	=	5.97	hr	ALA4324058			hr
7.	ALA4474912	61	CL	=	3.71	L/hr/kg	ALA4324057			mL.min-1.kg-1
8.	ALA4474912	61	AUCt	=	12871	ng/mL.hr	ALA4324056			ng.hr.mL-1
9.	ALA4474912	61	Vz	=	32	L/Kg	ALA4324055			L.kg-1	Mus musculus
10.	ALA4474912	61	Tmax	=	15	min	ALA4324054			hr
11.	ALA4474912	61	Cmax	=	6830	ng/ml	ALA4324053		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
12.	ALA4474912	61	t1/2	=	14	min	ALA4324052			hr
13.	ALA4474912	61	solubility	=	1.16	mg/ml	ALA4324051			ug.mL-1
14.	ALA4474912	61	EC50	=	3	uM	ALA4324046	5.52		nM	Homo sapiens
15.	ALA4474912	61	EC50	=	2.4	uM	ALA4324045	5.62		nM	Homo sapiens
16.	ALA4474912	61	EC50	=	17.4	uM	ALA4324044	4.76		nM	Homo sapiens
17.	ALA4474912	61	IC50	=	2.5	uM	ALA4324043	5.60		nM	Homo sapiens
18.	ALA4474912	61	IC50	=	4.1	uM	ALA4324042	5.39		nM	Homo sapiens
19.	ALA4474912	61	INH	=	83	%	ALA4324041			%	Homo sapiens