Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4474918	34a	Ratio	=	32		ALA4348373				Staphylococcus aureus
2.	ALA4474918	34a	Ratio	=	32		ALA4348372				Streptococcus pyogenes
3.	ALA4474918	34a	Ratio	=	0.4		ALA4348370				Rattus norvegicus
4.	ALA4474918	34a	Ratio	=	5		ALA4348369				Rattus norvegicus
5.	ALA4474918	34a	Ratio	=	1.4		ALA4348368
6.	ALA4474918	34a	Ratio	=	2.4		ALA4348367				Rattus norvegicus
7.	ALA4474918	34a	Ratio	=	7		ALA4348366				Rattus norvegicus
8.	ALA4474918	34a	Ratio	=	7		ALA4348365				Rattus norvegicus
9.	ALA4474918	34a	IC50	=	2.5	uM	ALA4348364	5.60		nM	Homo sapiens
10.	ALA4474918	34a	Cmax	=	1029	ng/ml	ALA4348363		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
11.	ALA4474918	34a	Tmax	=	0.833	hr	ALA4348362			hr
12.	ALA4474918	34a	MRT	=	4.53	hr	ALA4348361			hr
13.	ALA4474918	34a	t1/2	=	2.94	hr	ALA4348360			hr
14.	ALA4474918	34a	CL	=	3034	ml/hr/kg	ALA4348359			mL.min-1.kg-1
15.	ALA4474918	34a	AUCt	=	6731	hr.ng/ml	ALA4348358			ng.hr.mL-1
16.	ALA4474918	34a	AUC	=	6756	hr.ng/ml	ALA4348357			ng.hr.mL-1
17.	ALA4474918	34a	Activity	<=	3	log10CFU	ALA4348354			log10CFU	Streptococcus pyogenes
18.	ALA4474918	34a	Activity		0		ALA4348353		Active		Streptococcus pyogenes
19.	ALA4474918	34a	Ratio	=	32		ALA4348371				Streptococcus pneumoniae
20.	ALA4474918	34a	Activity		0		ALA4348352		Active		Streptococcus pneumoniae