| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4474982 | 25 | Drug metabolism | 0 | ALA4339685 | Metabolite_Detected | ||||||
| 2. | ALA4474982 | 25 | Drug metabolism | 0 | ALA4339684 | Metabolite_Detected | ||||||
| 3. | ALA4474982 | 25 | Drug metabolism | 0 | ALA4339683 | Metabolite_Detected | ||||||
| 4. | ALA4474982 | 25 | Tmax | = | 0.25 | hr | ALA4339676 | hr | ||||
| 5. | ALA4474982 | 25 | Cmax | = | 818 | ng/mg | ALA4339678 | ng/mg | ||||
| 6. | ALA4474982 | 25 | Occ | = | 32 | % | ALA4339675 | % | Rattus norvegicus | |||
| 7. | ALA4474982 | 25 | Occ | = | 69 | % | ALA4339674 | % | Rattus norvegicus | |||
| 8. | ALA4474982 | 25 | Occ | = | 77 | % | ALA4339673 | % | Rattus norvegicus | |||
| 9. | ALA4474982 | 25 | Tmax | = | 0.25 | hr | ALA4339671 | hr | ||||
| 10. | ALA4474982 | 25 | AUC | = | 571 | hr.ng/ml | ALA4339670 | ng.hr.mL-1 | ||||
| 11. | ALA4474982 | 25 | Cmax | = | 546 | ng/ml | ALA4339669 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 12. | ALA4474982 | 25 | Vdss | = | 0.5 | L/Kg | ALA4339668 | L.kg-1 | ||||
| 13. | ALA4474982 | 25 | CL | = | 48 | ml/min.kg | ALA4339667 | mL.min-1.kg-1 | ||||
| 14. | ALA4474982 | 25 | Ratio | = | 4.1 | ALA4339666 | ||||||
| 15. | ALA4474982 | 25 | IC50 | > | 10 | uM | ALA4339665 | nM | Homo sapiens | |||
| 16. | ALA4474982 | 25 | ERH | = | 0.68 | ALA4339664 | ||||||
| 17. | ALA4474982 | 25 | IC50 | > | 10 | uM | ALA4339663 | nM | Homo sapiens | |||
| 18. | ALA4474982 | 25 | IC50 | > | 10 | uM | ALA4339662 | nM | Homo sapiens | |||
| 19. | ALA4474982 | 25 | IC50 | > | 10 | uM | ALA4339661 | nM | Homo sapiens | |||
| 20. | ALA4474982 | 25 | IC50 | > | 10 | uM | ALA4339660 | nM | Homo sapiens |
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