# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4475183 | A6 | Activity | 0 | ALA4401445 | Dose-dependent effect | Cryptococcus neoformans | |||||
2. | ALA4475183 | A6 | GI | = | 100 | % | ALA4401486 | % | Cryptococcus neoformans | |||
3. | ALA4475183 | A6 | solubility | = | 57.5 | ug ml-1 | ALA4401485 | ug.mL-1 | ||||
4. | ALA4475183 | A6 | CLH | = | 477 | ml/min/mg | ALA4401464 | mL.min-1.g-1 | ||||
5. | ALA4475183 | A6 | t1/2 | = | 11 | min | ALA4401463 | hr | ||||
6. | ALA4475183 | A6 | INH | 0 | ALA4401462 | Not Active | % | Cryptococcus neoformans | ||||
7. | ALA4475183 | A6 | INH | 0 | ALA4401461 | Active | % | Cryptococcus neoformans | ||||
8. | ALA4475183 | A6 | Activity | 0 | ALA4401458 | Active | Cryptococcus neoformans | |||||
9. | ALA4475183 | A6 | Activity | 0 | ALA4401457 | Non-Toxic | Homo sapiens | |||||
10. | ALA4475183 | A6 | PPB | 0 | ALA4401456 | Active | % | |||||
11. | ALA4475183 | A6 | MIC80 | = | 2 | ug ml-1 | ALA4401455 | ug.mL-1 | Cryptococcus gattii | |||
12. | ALA4475183 | A6 | MIC80 | = | 2 | ug ml-1 | ALA4401454 | ug.mL-1 | Cryptococcus neoformans | |||
13. | ALA4475183 | A6 | MIC80 | = | 8 | ug ml-1 | ALA4401453 | ug.mL-1 | Nannizzia gypsea | |||
14. | ALA4475183 | A6 | MIC80 | = | 4 | ug ml-1 | ALA4401452 | ug.mL-1 | Trichophyton rubrum | |||
15. | ALA4475183 | A6 | MIC80 | = | 8 | ug ml-1 | ALA4401451 | ug.mL-1 | Aspergillus fumigatus | |||
16. | ALA4475183 | A6 | MIC80 | = | 8 | ug ml-1 | ALA4401450 | ug.mL-1 | Candida parapsilosis | |||
17. | ALA4475183 | A6 | MIC80 | = | 4 | ug ml-1 | ALA4401449 | ug.mL-1 | Candida albicans | |||
18. | ALA4475183 | A6 | MIC80 | = | 4 | ug ml-1 | ALA4401448 | ug.mL-1 | Candida albicans | |||
19. | ALA4475183 | A6 | MIC80 | = | 2 | ug ml-1 | ALA4401447 | ug.mL-1 | Cryptococcus neoformans | |||
20. | ALA4475183 | A6 | MIC80 | = | 2 | ug ml-1 | ALA4401446 | ug.mL-1 | Nakaseomyces glabratus |