# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4475207 | 34 | IC50 | = | 250 | nM | ALA4667953 | 6.60 | nM | Plasmodium falciparum | ||
2. | ALA4475207 | 34 | F | = | 13 | % | ALA4392045 | % | ||||
3. | ALA4475207 | 34 | Vz | = | 3.2 | L/Kg | ALA4392044 | L.kg-1 | ||||
4. | ALA4475207 | 34 | CL(app) | = | 5.9 | ml/min.kg | ALA4392042 | mL.min-1.kg-1 | ||||
5. | ALA4475207 | 34 | t1/2 | = | 6.6 | hr | ALA4392040 | hr | ||||
6. | ALA4475207 | 34 | CLH | = | 3.1 | microL/min/mg | ALA4392038 | mL.min-1.g-1 | ||||
7. | ALA4475207 | 34 | Ratio IC50 | = | 94 | ALA4392037 | ||||||
8. | ALA4475207 | 34 | IC50 | = | 21700 | nM | ALA4392036 | 4.66 | nM | Homo sapiens | ||
9. | ALA4475207 | 34 | IC50 | > | 10000 | nM | ALA4392032 | nM | Plasmodium falciparum | |||
10. | ALA4475207 | 34 | IC50 | > | 10000 | nM | ALA4392031 | nM | Plasmodium falciparum | |||
11. | ALA4475207 | 34 | IC50 | > | 10000 | nM | ALA4392030 | nM | Homo sapiens | |||
12. | ALA4475207 | 34 | t1/2 | = | 70 | min | ALA4392027 | hr | ||||
13. | ALA4475207 | 34 | IC50 | = | 116 | nM | ALA4392025 | 6.94 | nM | Plasmodium falciparum | ||
14. | ALA4475207 | 34 | IC50 | = | 230 | nM | ALA4392025 | 6.64 | nM | Plasmodium falciparum |