# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4475667 | 25 | CL free | = | 487 | L/hr/kg | ALA4324218 | mL.min-1.kg-1 | ||||
2. | ALA4475667 | 25 | CL | = | 0.5 | L/hr/kg | ALA4324217 | mL.min-1.kg-1 | ||||
3. | ALA4475667 | 25 | Fu | = | 0.17 | % | ALA4324216 | |||||
4. | ALA4475667 | 25 | Fu | = | 0.1 | % | ALA4324215 | |||||
5. | ALA4475667 | 25 | CLH | = | 11 | ml/min.kg | ALA4324214 | mL.min-1.kg-1 | ||||
6. | ALA4475667 | 25 | CLH | = | 53 | ml/min.kg | ALA4324213 | mL.min-1.kg-1 | ||||
7. | ALA4475667 | 25 | Ratio | = | 9.4 | ALA4324212 | ||||||
8. | ALA4475667 | 25 | Papp | = | 1.7 | 10'-6 cm/s | ALA4324211 | 10'-6 cm/s | ||||
9. | ALA4475667 | 25 | IC50 | = | 25 | nM | ALA4324210 | 7.60 | nM | Homo sapiens | ||
10. | ALA4475667 | 25 | IC50 | = | 5 | nM | ALA4324209 | 8.30 | nM | Homo sapiens |