| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4475680 | 21 | Time | 0 | ALA4417043 | Not Determined | Homo sapiens | |||||
| 2. | ALA4475680 | 21 | Kd | 0 | ALA4417042 | Not Determined | Homo sapiens | |||||
| 3. | ALA4475680 | 21 | T/C | = | 45 | % | ALA4417069 | % | Homo sapiens | |||
| 4. | ALA4475680 | 21 | Drug recovery | = | 23 | % | ALA4417036 | % | ||||
| 5. | ALA4475680 | 21 | t1/2 | = | 3 | hr | ALA4417057 | hr | ||||
| 6. | ALA4475680 | 21 | Vdss | = | 0.78 | L/Kg | ALA4417056 | L.kg-1 | ||||
| 7. | ALA4475680 | 21 | CL | = | 0.18 | L/hr/kg | ALA4417055 | mL.min-1.kg-1 | ||||
| 8. | ALA4475680 | 21 | Ratio | = | 0.08 | ALA4417054 | ||||||
| 9. | ALA4475680 | 21 | AUC | = | 19 | ng/mL.hr | ALA4417053 | ng.hr.mL-1 | ||||
| 10. | ALA4475680 | 21 | Fu | = | 2.3 | % | ALA4417052 | |||||
| 11. | ALA4475680 | 21 | Fu | = | 1.7 | % | ALA4417051 | |||||
| 12. | ALA4475680 | 21 | Ratio | = | 5 | ALA4417050 | ||||||
| 13. | ALA4475680 | 21 | permeability | = | 16 | 10'-6 cm/s | ALA4417049 | 10'-6 cm/s | ||||
| 14. | ALA4475680 | 21 | solubility | = | 90 | ug ml-1 | ALA4417048 | ug.mL-1 | ||||
| 15. | ALA4475680 | 21 | Drug recovery | 0 | ALA4417047 | Active | ||||||
| 16. | ALA4475680 | 21 | Drug recovery | 0 | ALA4417046 | Active | ||||||
| 17. | ALA4475680 | 21 | Activity | >= | 50 | % | ALA4417044 | % | Homo sapiens | |||
| 18. | ALA4475680 | 21 | Ki | = | 0.16 | nM | ALA4417041 | 9.80 | nM | Homo sapiens | ||
| 19. | ALA4475680 | 21 | IC50 | > | 10 | uM | ALA4417040 | nM | Homo sapiens | |||
| 20. | ALA4475680 | 21 | IC50 | = | 15 | nM | ALA4417039 | 7.82 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!