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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4475854	5a	INH		0		ALA4345890		Dose-dependent effect	%	Mus musculus
2.	ALA4475854	5a	t1/2	=	3.9	hr	ALA4345889			hr
3.	ALA4475854	5a	t1/2	=	3.6	hr	ALA4345888			hr
4.	ALA4475854	5a	Vdss	=	0.8	L/Kg	ALA4345887			L.kg-1
5.	ALA4475854	5a	CL free	=	1.1	L/hr/kg	ALA4345886			mL.min-1.kg-1
6.	ALA4475854	5a	CL	=	0.15	L/hr/kg	ALA4345885			mL.min-1.kg-1
7.	ALA4475854	5a	AUC	=	15000	nM.hr	ALA4345884		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW	ng.hr.mL-1
8.	ALA4475854	5a	F	=	120	%	ALA4345883			%
9.	ALA4475854	5a	Papp	=	51	10'-6 cm/s	ALA4345882			10'-6 cm/s
10.	ALA4475854	5a	Papp	=	31	10'-6 cm/s	ALA4345881			10'-6 cm/s
11.	ALA4475854	5a	solubility	=	170	uM	ALA4345880			nM
12.	ALA4475854	5a	PPB	=	86.5	%	ALA4345879			%
13.	ALA4475854	5a	PPB	=	91.8	%	ALA4345878			%
14.	ALA4475854	5a	CLH	=	0.03	ml/min/mg	ALA4345877			mL.min-1.g-1
15.	ALA4475854	5a	CLH	=	0.01	ml/min/mg	ALA4345876			mL.min-1.g-1
16.	ALA4475854	5a	IC50	=	51	nM	ALA4345875	7.29		nM	Homo sapiens
17.	ALA4475854	5a	IC50	=	130	nM	ALA4345894	6.89		nM	Homo sapiens
18.	ALA4475854	5a	INH		0		ALA4345894		Dose-dependent effect	%	Homo sapiens