# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4475943 | (S)-14b | Vdss | = | 80 | L/Kg | ALA4329656 | L.kg-1 | ||||
2. | ALA4475943 | (S)-14b | t1/2 | = | 3.63 | hr | ALA4329655 | hr | ||||
3. | ALA4475943 | (S)-14b | CLH | = | 340 | ml/min.kg | ALA4329654 | mL.min-1.kg-1 | ||||
4. | ALA4475943 | (S)-14b | Fu | = | 0.004 | % | ALA4329653 | |||||
5. | ALA4475943 | (S)-14b | Fu | = | 0.124 | % | ALA4329652 | |||||
6. | ALA4475943 | (S)-14b | IC50 | = | 21 | nM | ALA4329649 | 7.68 | nM | Homo sapiens | ||
7. | ALA4475943 | (S)-14b | IC50 | = | 2.5 | nM | ALA4329650 | 8.60 | nM | Homo sapiens | ||
8. | ALA4475943 | (S)-14b | Fu | = | 0.198 | % | ALA4329651 |