| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4475961 | 3 | pKa | = | 9.5 | ALA4729970 | ||||||
| 2. | ALA4475961 | 3 | CL | = | 22 | ml/min.kg | ALA4729969 | mL.min-1.kg-1 | ||||
| 3. | ALA4475961 | 3 | AUC/dose | = | 206 | nmol.hr/L | ALA4729968 | nmol.hr/L | ||||
| 4. | ALA4475961 | 3 | F | = | 10 | % | ALA4729966 | % | ||||
| 5. | ALA4475961 | 3 | pKA | = | 4 | ALA4729964 | ||||||
| 6. | ALA4475961 | 3 | IC50 | = | 2.8 | uM | ALA4729963 | 5.55 | nM | Homo sapiens | ||
| 7. | ALA4475961 | 3 | IC50 | = | 0.12 | uM | ALA4729962 | 6.92 | nM | Homo sapiens | ||
| 8. | ALA4475961 | 3 | log(permeability) | < | -5.3 | ALA4729961 | ||||||
| 9. | ALA4475961 | 3 | IC50 | = | 27 | uM | ALA4729958 | 4.57 | nM | Homo sapiens | ||
| 10. | ALA4475961 | 3 | F | = | 10 | % | ALA4394738 | % | ||||
| 11. | ALA4475961 | 3 | CL | = | 22 | ml/min.Kg | ALA4394735 | mL.min-1.kg-1 | ||||
| 12. | ALA4475961 | 3 | solubility | = | 0.22 | mM | ALA4394737 | nM | ||||
| 13. | ALA4475961 | 3 | Ratio IC50 | = | 19 | ALA4394739 | ||||||
| 14. | ALA4475961 | 3 | Ratio IC50 | = | 23 | ALA4394740 | ||||||
| 15. | ALA4475961 | 3 | IC50 | = | 2.3 | uM | ALA4394744 | 5.64 | nM | Homo sapiens | ||
| 16. | ALA4475961 | 3 | IC50 | = | 2.8 | uM | ALA4394743 | 5.55 | nM | Homo sapiens | ||
| 17. | ALA4475961 | 3 | logPapp | < | -5.3 | ALA4394742 | ||||||
| 18. | ALA4475961 | 3 | IC50 | = | 4.8 | uM | ALA4394741 | 5.32 | nM | Homo sapiens | ||
| 19. | ALA4475961 | 3 | IC50 | = | 0.12 | uM | ALA4394736 | 6.92 | nM | Homo sapiens | ||
| 20. | ALA4475961 | 3 | IC50 | = | 0.12 | uM | ALA4621383 | 6.92 | nM | Homo sapiens |
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