# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4476185 | 26 | Stability | = | 89 | % | ALA4350023 | % | ||||
2. | ALA4476185 | 26 | Stability | = | 83 | % | ALA4350022 | % | ||||
3. | ALA4476185 | 26 | Stability | = | 85 | % | ALA4350021 | % | ||||
4. | ALA4476185 | 26 | IC50 | > | 30 | uM | ALA4350008 | nM | Homo sapiens | |||
5. | ALA4476185 | 26 | F | = | 45 | % | ALA4349966 | % | ||||
6. | ALA4476185 | 26 | t1/2 | = | 3.2 | hr | ALA4349965 | hr | ||||
7. | ALA4476185 | 26 | CL | = | 9.6 | ml/min.kg | ALA4349964 | mL.min-1.kg-1 | ||||
8. | ALA4476185 | 26 | Vdss | = | 2.5 | L/Kg | ALA4349963 | L.kg-1 | ||||
9. | ALA4476185 | 26 | AUC | = | 19.6 | uM.hr | ALA4349962 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
10. | ALA4476185 | 26 | Tmax | = | 0.25 | hr | ALA4349961 | hr | ||||
11. | ALA4476185 | 26 | Cmax | = | 18.3 | uM | ALA4349960 | nM | ||||
12. | ALA4476185 | 26 | INH | = | 56 | % | ALA4349934 | % | Mus musculus | |||
13. | ALA4476185 | 26 | INH | = | 49 | % | ALA4349933 | % | Mus musculus | |||
14. | ALA4476185 | 26 | INH | = | 3 | % | ALA4349932 | % | Mus musculus | |||
15. | ALA4476185 | 26 | solubility | > | 2000 | uM | ALA4349929 | nM | ||||
16. | ALA4476185 | 26 | solubility | = | 1 | uM | ALA4349928 | nM | ||||
17. | ALA4476185 | 26 | solubility | = | 1 | uM | ALA4349927 | nM | ||||
18. | ALA4476185 | 26 | IC50 | 0 | ALA4349926 | Not Determined | Homo sapiens | |||||
19. | ALA4476185 | 26 | IC50 | > | 50 | uM | ALA4349925 | nM | Homo sapiens | |||
20. | ALA4476185 | 26 | IC50 | > | 50 | uM | ALA4349924 | nM | Homo sapiens |