| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4476462 | 7 | INH | 0 | ALA4324048 | Active | % | Homo sapiens | ||||
| 2. | ALA4476462 | 7 | INH | 0 | ALA4324047 | Active | % | Homo sapiens | ||||
| 3. | ALA4476462 | 7 | Activity | 0 | ALA4324059 | Active | Homo sapiens | |||||
| 4. | ALA4476462 | 7 | t1/2lambda | = | 1.96 | hr | ALA4324058 | hr | ||||
| 5. | ALA4476462 | 7 | CL | = | 3.87 | L/hr/kg | ALA4324057 | mL.min-1.kg-1 | ||||
| 6. | ALA4476462 | 7 | AUCt | = | 12488 | ng/mL.hr | ALA4324056 | ng.hr.mL-1 | ||||
| 7. | ALA4476462 | 7 | Vz | = | 10.9 | L/Kg | ALA4324055 | L.kg-1 | Mus musculus | |||
| 8. | ALA4476462 | 7 | Tmax | = | 15 | min | ALA4324054 | hr | ||||
| 9. | ALA4476462 | 7 | Cmax | = | 18986 | ng/ml | ALA4324053 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 10. | ALA4476462 | 7 | t1/2 | = | 6.72 | min | ALA4324052 | hr | ||||
| 11. | ALA4476462 | 7 | solubility | = | 0.45 | mg/ml | ALA4324051 | ug.mL-1 | ||||
| 12. | ALA4476462 | 7 | Drug metabolism | 0 | ALA4324060 | Metabolite_Detected | ||||||
| 13. | ALA4476462 | 7 | Stability | 0 | ALA4324061 | Stable | % | |||||
| 14. | ALA4476462 | 7 | Drug metabolism | 0 | ALA4324065 | Metabolite_Notdetected | ||||||
| 15. | ALA4476462 | 7 | Activity | 0 | ALA4324050 | Active | Homo sapiens | |||||
| 16. | ALA4476462 | 7 | GI | 0 | ALA4324049 | Active | Homo sapiens | |||||
| 17. | ALA4476462 | 7 | EC50 | = | 1.6 | uM | ALA4324046 | 5.80 | nM | Homo sapiens | ||
| 18. | ALA4476462 | 7 | EC50 | = | 1.2 | uM | ALA4324045 | 5.92 | nM | Homo sapiens | ||
| 19. | ALA4476462 | 7 | EC50 | > | 30 | uM | ALA4324044 | nM | Homo sapiens | |||
| 20. | ALA4476462 | 7 | IC50 | = | 2.4 | uM | ALA4324043 | 5.62 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!