# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | AZD0364 (ATG-017) | 15; AZD0364 | Fu | = | 6 | % | ALA4324337 | |||||
2. | AZD0364 (ATG-017) | 15; AZD0364 | Fu | = | 44 | % | ALA4324336 | |||||
3. | AZD0364 (ATG-017) | 15; AZD0364 | Fu | = | 21 | % | ALA4324335 | |||||
4. | AZD0364 (ATG-017) | 15; AZD0364 | Fu | = | 12 | % | ALA4324334 | |||||
5. | AZD0364 (ATG-017) | 15; AZD0364 | GI50 | = | 0.2 | uM | ALA4324306 | nM | Homo sapiens | |||
6. | AZD0364 (ATG-017) | 15; AZD0364 | GI50 | = | 0.06 | uM | ALA4324305 | nM | Homo sapiens | |||
7. | AZD0364 (ATG-017) | 15; AZD0364 | F | = | 100 | % | ALA4324345 | % | ||||
8. | AZD0364 (ATG-017) | 15; AZD0364 | F | = | 30 | % | ALA4324344 | % | ||||
9. | AZD0364 (ATG-017) | 15; AZD0364 | t1/2 | = | 5 | hr | ALA4324343 | hr | ||||
10. | AZD0364 (ATG-017) | 15; AZD0364 | t1/2 | = | 2.3 | hr | ALA4324342 | hr | ||||
11. | AZD0364 (ATG-017) | 15; AZD0364 | Vdss | = | 1.2 | L/Kg | ALA4324341 | L.kg-1 | ||||
12. | AZD0364 (ATG-017) | 15; AZD0364 | Vdss | = | 1.5 | L/Kg | ALA4324340 | L.kg-1 | ||||
13. | AZD0364 (ATG-017) | 15; AZD0364 | CL | = | 12 | uL/min/kg | ALA4324339 | mL.min-1.kg-1 | ||||
14. | AZD0364 (ATG-017) | 15; AZD0364 | CL | = | 38 | uL/min/kg | ALA4324338 | mL.min-1.kg-1 | ||||
15. | AZD0364 (ATG-017) | 15; AZD0364 | Activity | = | 28 | % | ALA4324333 | % | Homo sapiens | |||
16. | AZD0364 (ATG-017) | 15; AZD0364 | INH | = | 100 | % | ALA4324332 | % | Mus musculus | |||
17. | AZD0364 (ATG-017) | 15; AZD0364 | INH | = | 100 | % | ALA4324331 | % | Mus musculus | |||
18. | AZD0364 (ATG-017) | 15; AZD0364 | Activity | = | 49 | % | ALA4324330 | % | Homo sapiens | |||
19. | AZD0364 (ATG-017) | 15; AZD0364 | TGI | = | 93 | % | ALA4324329 | % | Homo sapiens | |||
20. | AZD0364 (ATG-017) | 15; AZD0364 | INH | = | 80 | % | ALA4324328 | % | Homo sapiens |