# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4482878 | 36 | IC50 | = | 6.8 | nM | ALA4329743 | 8.17 | nM | Homo sapiens | ||
2. | ALA4482878 | 36 | IC50 | = | 8.7 | nM | ALA4329744 | 8.06 | nM | Homo sapiens | ||
3. | ALA4482878 | 36 | AUC | = | 18000 | nM.hr | ALA4329747 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
4. | ALA4482878 | 36 | IC50 | = | 22 | nM | ALA4329749 | 7.66 | nM | Homo sapiens | ||
5. | ALA4482878 | 36 | IC50 | = | 4000 | nM | ALA4329750 | 5.40 | nM | Homo sapiens | ||
6. | ALA4482878 | 36 | IC50 | > | 8000 | nM | ALA4329751 | nM | Homo sapiens | |||
7. | ALA4482878 | 36 | PPB | = | 98 | % | ALA4329752 | % | ||||
8. | ALA4482878 | 36 | PPB | = | 80.8 | % | ALA4329753 | % | ||||
9. | ALA4482878 | 36 | Cmax | = | 17000 | nM | ALA4329754 | nM | ||||
10. | ALA4482878 | 36 | INH | 0 | ALA4329755 | Active | % | Homo sapiens | ||||
11. | ALA4482878 | 36 | INH | 0 | ALA4329756 | Active | % | Homo sapiens | ||||
12. | ALA4482878 | 36 | Activity | 0 | ALA4329757 | Not Active | Homo sapiens | |||||
13. | ALA4482878 | 36 | Activity | 0 | ALA4329758 | Not Active | Homo sapiens | |||||
14. | ALA4482878 | 36 | INH | 0 | ALA4329761 | Dose-dependent effect | % | Mus musculus | ||||
15. | ALA4482878 | 36 | INH | 0 | ALA4329762 | Active | % | Mus musculus | ||||
16. | ALA4482878 | 36 | INH | = | 50 | % | ALA4329763 | % | Mus musculus | |||
17. | ALA4482878 | 36 | INH | = | 74 | % | ALA4329764 | % | Mus musculus | |||
18. | ALA4482878 | 36 | Cp | = | 21 | uM | ALA4329765 | uM | ||||
19. | ALA4482878 | 36 | Cp | = | 70 | uM | ALA4329766 | uM |