Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4483558	43d	AUC	=	157	umol/l.hr	ALA4388140		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW \| standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW	ng.hr.mL-1
2.	ALA4483558	43d	t1/2	=	4.1	hr	ALA4388121			hr
3.	ALA4483558	43d	Cmax	=	5.35	umol/L	ALA4388120			nM
4.	ALA4483558	43d	FC	=	5.75		ALA4388139				Homo sapiens
5.	ALA4483558	43d	Ratio	=	18.8		ALA4388138
6.	ALA4483558	43d	Ratio	=	3.7		ALA4388137
7.	ALA4483558	43d	Activity		0		ALA4388136		Active		Homo sapiens
8.	ALA4483558	43d	GI50	>	10	uM	ALA4388135			nM	Homo sapiens
9.	ALA4483558	43d	GI50	=	0.25	uM	ALA4388134			nM	Homo sapiens
10.	ALA4483558	43d	Stability	=	19.1	%	ALA4388133			%
11.	ALA4483558	43d	Stability	=	28.9	%	ALA4388132			%
12.	ALA4483558	43d	Fu	=	4.2	%	ALA4388131
13.	ALA4483558	43d	Fu	=	1.8	%	ALA4388130
14.	ALA4483558	43d	permeability	=	1.1	10'-6 cm/s	ALA4388129			10'-6 cm/s
15.	ALA4483558	43d	solubility	=	84.5	ug ml-1	ALA4388128			ug.mL-1
16.	ALA4483558	43d	GI50	=	1	uM	ALA4388126			nM	Homo sapiens
17.	ALA4483558	43d	IC50	=	13.9	nM	ALA4388125	7.86		nM	Homo sapiens
18.	ALA4483558	43d	IC50	>	20000	nM	ALA4388124			nM	Homo sapiens
19.	ALA4483558	43d	IC50	=	6.8	nM	ALA4388123	8.17		nM	Homo sapiens
20.	ALA4483558	43d	IC50	=	4.4	nM	ALA4388122	8.36		nM	Homo sapiens