| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4513442 | 26 | INH | = | 88.3 | % | ALA4352656 | % | Rattus norvegicus | |||
| 2. | ALA4513442 | 26 | Activity | 0 | ALA4352657 | Dose-dependent effect | Rattus norvegicus | |||||
| 3. | ALA4513442 | 26 | ED50 | = | 0.25 | mg kg-1 | ALA4352657 | mg.kg-1 | Rattus norvegicus | |||
| 4. | ALA4513442 | 26 | Drug metabolism | 0 | ALA4352658 | Metabolite_Notdetected | ||||||
| 5. | ALA4513442 | 26 | AUC | = | 3261 | hr.ng/ml | ALA4352659 | ng.hr.mL-1 | ||||
| 6. | ALA4513442 | 26 | Vdss | = | 1.7 | L/Kg | ALA4352660 | L.kg-1 | ||||
| 7. | ALA4513442 | 26 | t1/2 | = | 6.3 | hr | ALA4352661 | hr | ||||
| 8. | ALA4513442 | 26 | CL | = | 5.4 | ml/min.kg | ALA4352662 | mL.min-1.kg-1 | ||||
| 9. | ALA4513442 | 26 | AUC | = | 13125 | hr.ng/ml | ALA4352665 | ng.hr.mL-1 | ||||
| 10. | ALA4513442 | 26 | Cmax | = | 2532 | ng/ml | ALA4352664 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA4513442 | 26 | F | = | 82.4 | % | ALA4352673 | % | ||||
| 12. | ALA4513442 | 26 | AUC | = | 3274 | hr.ng/ml | ALA4352672 | ng.hr.mL-1 | ||||
| 13. | ALA4513442 | 26 | Vdss | = | 1.2 | L/Kg | ALA4352671 | L.kg-1 | ||||
| 14. | ALA4513442 | 26 | t1/2 | = | 1.5 | hr | ALA4352670 | hr | ||||
| 15. | ALA4513442 | 26 | CL | = | 12.7 | ml/min.kg | ALA4352669 | mL.min-1.kg-1 | ||||
| 16. | ALA4513442 | 26 | AUC | = | 14342 | hr.ng/ml | ALA4352668 | ng.hr.mL-1 | ||||
| 17. | ALA4513442 | 26 | Cmax | = | 2730 | ng/ml | ALA4352667 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 18. | ALA4513442 | 26 | F | = | 107.9 | % | ALA4352666 | % | ||||
| 19. | ALA4513442 | 26 | INH | = | 87.9 | % | ALA4352663 | % | Rattus norvegicus | |||
| 20. | ALA4513442 | 26 | IC50 | = | 0.337 | uM | ALA4352655 | 6.47 | nM | Homo sapiens |
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