Activities

#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325813	Active	%	Human immunodeficiency virus 1
2.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325812	Active	%	Homo sapiens
3.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325811	Active	%	Homo sapiens
4.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325810	Not Active	%	Geobacillus stearothermophilus
5.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325809	Not Active	%
6.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325808	Not Active	%
7.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325807	Not Active	%	Carica papaya
8.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	Stability		0		ALA4325806	Stable	%	Geobacillus stearothermophilus
9.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	Stability		0		ALA4325805	Stable	%
10.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	Stability		0		ALA4325804	Stable	%
11.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	Stability		0		ALA4325803	Stable	%	Carica papaya
12.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325802	Active	%	Saccharomyces cerevisiae S288c
13.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325801	Active	%
14.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325800	Active	%	Homo sapiens
15.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325799	Not Active	%	Human immunodeficiency virus 1
16.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325798	Not Active	%	Homo sapiens
17.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	INH		0		ALA4325797	Not Active	%	Homo sapiens
18.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	Activity		0		ALA4325795	Non-Toxic		Homo sapiens
19.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	Activity		0		ALA4325794	Non-Toxic		Homo sapiens
20.	(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione	33	Papp	=	16.8	10'-7 cm/s	ALA4325793		10'-7 cm/s

1.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325813

Active

%

Human immunodeficiency virus 1

2.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325812

Active

%

Homo sapiens

3.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325811

Active

%

Homo sapiens

4.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325810

Not Active

%

Geobacillus stearothermophilus

5.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325809

Not Active

%

6.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325808

Not Active

%

7.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325807

Not Active

%

Carica papaya

8.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

Stability

0

ALA4325806

Stable

%

Geobacillus stearothermophilus

9.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

Stability

0

ALA4325805

Stable

%

10.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

Stability

0

ALA4325804

Stable

%

11.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

Stability

0

ALA4325803

Stable

%

Carica papaya

12.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325802

Active

%

Saccharomyces cerevisiae S288c

13.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325801

Active

%

14.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325800

Active

%

Homo sapiens

15.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325799

Not Active

%

Human immunodeficiency virus 1

16.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325798

Not Active

%

Homo sapiens

17.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

INH

0

ALA4325797

Not Active

%

Homo sapiens

18.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

Activity

0

ALA4325795

Non-Toxic

Homo sapiens

19.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

Activity

0

ALA4325794

Non-Toxic

Homo sapiens

20.

(4S,5S,9S)-4-Benzyl-5-hydroxy-9-isopropyl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione

33

Papp

=

16.8

10'-7 cm/s

ALA4325793

10'-7 cm/s