| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4514196 | 16 | t1/2 | > | 24 | hr | ALA4408576 | hr | ||||
| 2. | ALA4514196 | 16 | INH | = | 77 | % | ALA4408575 | % | Mus musculus | |||
| 3. | ALA4514196 | 16 | Activity | = | 21 | ALA4408574 | Mus musculus | |||||
| 4. | ALA4514196 | 16 | Activity | 0 | ALA4408573 | Active | Mus musculus | |||||
| 5. | ALA4514196 | 16 | INH | 0 | ALA4408572 | Dose-dependent effect | % | Mus musculus | ||||
| 6. | ALA4514196 | 16 | Activity | 0 | ALA4408570 | Active | Mus musculus | |||||
| 7. | ALA4514196 | 16 | Activity | 0 | ALA4408568 | Toxic | ||||||
| 8. | ALA4514196 | 16 | t1/2 | = | 0.91 | hr | ALA4408567 | hr | ||||
| 9. | ALA4514196 | 16 | F | = | 11 | % | ALA4408566 | % | ||||
| 10. | ALA4514196 | 16 | AUC | = | 902 | hr.ng/ml | ALA4408565 | ng.hr.mL-1 | ||||
| 11. | ALA4514196 | 16 | t1/2 | = | 0.66 | hr | ALA4408564 | hr | ||||
| 12. | ALA4514196 | 16 | Vd | = | 2.09 | L/Kg | ALA4408563 | L.kg-1 | ||||
| 13. | ALA4514196 | 16 | CL | = | 2.81 | L/hr/kg | ALA4408562 | mL.min-1.kg-1 | ||||
| 14. | ALA4514196 | 16 | solubility | = | 0.21 | mg/ml | ALA4408561 | ug.mL-1 | ||||
| 15. | ALA4514196 | 16 | Ratio | = | 1.07 | ALA4408560 | ||||||
| 16. | ALA4514196 | 16 | Papp | = | 2.9 | 10'-6 cm/s | ALA4408559 | 10'-6 cm/s | ||||
| 17. | ALA4514196 | 16 | IC50 | = | 3.96 | uM | ALA4408558 | 5.40 | nM | Homo sapiens | ||
| 18. | ALA4514196 | 16 | IC50 | = | 0.49 | uM | ALA4408557 | 6.31 | nM | Homo sapiens | ||
| 19. | ALA4514196 | 16 | IC50 | = | 104 | nM | ALA4408555 | 6.98 | nM | Homo sapiens | ||
| 20. | ALA4514196 | 16 | IC50 | = | 10.1 | nM | ALA4408554 | 8.00 | nM | Homo sapiens |
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