# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | Fisogatinib (BLU-554) | BLU554 | IC50 | = | 45.9 | nM | ALA5239772 | 7.34 | nM | Homo sapiens | ||
2. | Fisogatinib (BLU-554) | BLU554 | IC50 | = | 5.3 | nM | ALA5239771 | 8.28 | nM | Homo sapiens | ||
3. | Fisogatinib (BLU-554) | BLU554 | deltaG | = | -50.23 | kcal/mol | ALA5168187 | kcal/mol | Homo sapiens | |||
4. | Fisogatinib (BLU-554) | BLU554 | deltaG | = | -90.6 | kcal/mol | ALA5168186 | kcal/mol | Homo sapiens | |||
5. | Fisogatinib (BLU-554) | BLU554 | Ratio IC50 | > | 120 | ALA5168168 | ||||||
6. | Fisogatinib (BLU-554) | BLU554 | Ratio IC50 | > | 120 | ALA5168167 | ||||||
7. | Fisogatinib (BLU-554) | BLU554 | IC50 | > | 30 | uM | ALA5168166 | nM | Homo sapiens | |||
8. | Fisogatinib (BLU-554) | BLU554 | IC50 | > | 30 | uM | ALA5168161 | nM | Homo sapiens | |||
9. | Fisogatinib (BLU-554) | BLU554 | IC50 | > | 30 | uM | ALA5168160 | nM | Homo sapiens | |||
10. | Fisogatinib (BLU-554) | BLU554 | IC50 | > | 30 | uM | ALA5168159 | nM | Homo sapiens | |||
11. | Fisogatinib (BLU-554) | BLU554 | IC50 | > | 30 | uM | ALA5168158 | nM | Homo sapiens | |||
12. | Fisogatinib (BLU-554) | BLU554 | IC50 | = | 24.19 | uM | ALA5168157 | 4.62 | nM | Homo sapiens | ||
13. | Fisogatinib (BLU-554) | BLU554 | IC50 | = | 4.7 | uM | ALA5168156 | 5.33 | nM | Homo sapiens | ||
14. | Fisogatinib (BLU-554) | BLU554 | IC50 | = | 21.78 | uM | ALA5168155 | 4.66 | nM | Homo sapiens | ||
15. | Fisogatinib (BLU-554) | BLU554 | IC50 | > | 30 | uM | ALA5168154 | nM | Homo sapiens | |||
16. | Fisogatinib (BLU-554) | BLU554 | PPB | = | 99.4 | % | ALA5168153 | % | ||||
17. | Fisogatinib (BLU-554) | BLU554 | PPB | = | 98 | % | ALA5168152 | % | ||||
18. | Fisogatinib (BLU-554) | BLU554 | t1/2 | > | 289.1 | min | ALA5168151 | hr | ||||
19. | Fisogatinib (BLU-554) | BLU554 | t1/2 | > | 289.1 | min | ALA5168150 | hr | ||||
20. | Fisogatinib (BLU-554) | BLU554 | t1/2 | > | 289.1 | min | ALA5168149 | hr |