Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	GSK2983559 active metabolite	5	IC50	>	50	uM	ALA4394511			nM
2.	GSK2983559 active metabolite	5	INH	=	0	%	ALA4394510			%	Homo sapiens
3.	GSK2983559 active metabolite	5	IC50	>	50000	nM	ALA4394508			nM	Homo sapiens
4.	GSK2983559 active metabolite	5	IC50	=	30	uM	ALA4394505	4.52		nM
5.	GSK2983559 active metabolite	5	IC50	>	50	uM	ALA4394504			nM
6.	GSK2983559 active metabolite	5	permeability	=	166	nm/s	ALA4367429			nm/s
7.	GSK2983559 active metabolite	5	IC50	=	10	nM	ALA4367471	8.00		nM	Homo sapiens
8.	GSK2983559 active metabolite	5	IC50	=	10	nM	ALA4367470	8.00		nM	Homo sapiens
9.	GSK2983559 active metabolite	5	IC50	=	10	nM	ALA4367469	8.00		nM	Homo sapiens
10.	GSK2983559 active metabolite	5	IC50	=	10	nM	ALA4367468	8.00		nM	Homo sapiens
11.	GSK2983559 active metabolite	5	INH		0		ALA4367439		Dose-dependent effect	%	Homo sapiens
12.	GSK2983559 active metabolite	5	INH		0		ALA4367438		Dose-dependent effect	%	Homo sapiens
13.	GSK2983559 active metabolite	5	Activity		0		ALA4367471		Dose-dependent effect		Homo sapiens
14.	GSK2983559 active metabolite	5	Activity		0		ALA4367470		Dose-dependent effect		Homo sapiens
15.	GSK2983559 active metabolite	5	Activity		0		ALA4367469		Dose-dependent effect		Homo sapiens
16.	GSK2983559 active metabolite	5	Activity		0		ALA4367468		Dose-dependent effect		Homo sapiens
17.	GSK2983559 active metabolite	5	Activity		0		ALA4367456		Not Active		Homo sapiens
18.	GSK2983559 active metabolite	5	Activity		0		ALA4367455		Not Active		Homo sapiens
19.	GSK2983559 active metabolite	5	CLH	<	0.48	ml/min/g	ALA4367454			mL.min-1.g-1
20.	GSK2983559 active metabolite	5	CLH	=	0.55	ml/min/g	ALA4367453			mL.min-1.g-1