Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4516721	34j	Drug uptake	=	1060	ng/g	ALA4311725			ng/g
2.	ALA4516721	34j	Drug uptake	=	1.2	%	ALA4311728			%
3.	ALA4516721	34j	Drug uptake	=	12.5	ng/g	ALA4311727			ng/g
4.	ALA4516721	34j	Drug uptake	=	83.8	ng/g	ALA4311726			ng/g
5.	ALA4516721	34j	Drugexcretion	=	89.8	%ID	ALA4311721			%ID
6.	ALA4516721	34j	Drugexcretion	=	5.3	%ID	ALA4311719			%ID
7.	ALA4516721	34j	F	=	0.09	%	ALA4311717			%
8.	ALA4516721	34j	Tmax	=	0.25	hr	ALA4311716			hr
9.	ALA4516721	34j	Cmax	=	5.34	ng/ml	ALA4311715		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
10.	ALA4516721	34j	t1/2	=	0.578	hr	ALA4311714			hr
11.	ALA4516721	34j	Vdss	=	964	ml/kg	ALA4311713			L.kg-1
12.	ALA4516721	34j	CL	=	3760	ml/hr/kg	ALA4311712			mL.min-1.kg-1
13.	ALA4516721	34j	permeability	=	0	10'-6 cm/s	ALA4311711			10'-6 cm/s
14.	ALA4516721	34j	IC50	=	64	nM	ALA4311710	7.19		nM	Homo sapiens
15.	ALA4516721	34j	IC50	=	27	nM	ALA4311709	7.57		nM	Homo sapiens