# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | AES-135 | 5; AES-135 | logD | = | 4.15 | ALA4401706 | ||||||
2. | AES-135 | 5; AES-135 | INH | = | 98 | % | ALA4401647 | % | Homo sapiens | |||
3. | AES-135 | 5; AES-135 | t1/2 | = | 38.5 | min | ALA4401666 | hr | ||||
4. | AES-135 | 5; AES-135 | Activity | 0 | ALA4401713 | Not Active | ||||||
5. | AES-135 | 5; AES-135 | Activity | 0 | ALA4401712 | Non-Toxic | ||||||
6. | AES-135 | 5; AES-135 | F | = | 100 | % | ALA4401711 | % | ||||
7. | AES-135 | 5; AES-135 | CL | = | 0.004 | L/hr | ALA4401710 | L/hr | ||||
8. | AES-135 | 5; AES-135 | t1/2 | = | 5 | hr | ALA4401709 | hr | ||||
9. | AES-135 | 5; AES-135 | Tmax | = | 8 | hr | ALA4401708 | hr | ||||
10. | AES-135 | 5; AES-135 | Cmax | = | 10.74 | uM | ALA4401707 | nM | ||||
11. | AES-135 | 5; AES-135 | Drug recovery | = | 16 | % | ALA4401705 | % | ||||
12. | AES-135 | 5; AES-135 | PPB | = | 99.6 | % | ALA4401704 | % | ||||
13. | AES-135 | 5; AES-135 | INH | 0 | ALA4401703 | Not Active | % | Homo sapiens | ||||
14. | AES-135 | 5; AES-135 | INH | 0 | ALA4401702 | Not Active | % | Homo sapiens | ||||
15. | AES-135 | 5; AES-135 | INH | 0 | ALA4401701 | Not Active | % | Homo sapiens | ||||
16. | AES-135 | 5; AES-135 | INH | 0 | ALA4401700 | Not Active | % | Homo sapiens | ||||
17. | AES-135 | 5; AES-135 | INH | 0 | ALA4401699 | Not Active | % | Homo sapiens | ||||
18. | AES-135 | 5; AES-135 | INH | 0 | ALA4401698 | Not Active | % | Homo sapiens | ||||
19. | AES-135 | 5; AES-135 | Stability | 0 | ALA4401697 | Stable | % | |||||
20. | AES-135 | 5; AES-135 | MST | = | 36.5 | day | ALA4401696 | day |