# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4521157 | Table 1, cpd 2 | Activity | 0 | ALA4383913 | Not Active | Rattus norvegicus | |||||
2. | ALA4521157 | Table 1, cpd 2 | Activity | = | 19.9 | mmHg | ALA4383912 | mmHg | Mus musculus | |||
3. | ALA4521157 | Table 1, cpd 2 | FC | = | 4.7 | ALA4383911 | Mus musculus | |||||
4. | ALA4521157 | Table 1, cpd 2 | FC | = | 3.9 | ALA4383910 | Mus musculus | |||||
5. | ALA4521157 | Table 1, cpd 2 | FC | = | 4.6 | ALA4383909 | Mus musculus | |||||
6. | ALA4521157 | Table 1, cpd 2 | MRT | = | 6 | hr | ALA4383908 | hr | ||||
7. | ALA4521157 | Table 1, cpd 2 | Drug uptake | = | 65 | % | ALA4383907 | % | ||||
8. | ALA4521157 | Table 1, cpd 2 | F | = | 15 | % | ALA4383906 | % | ||||
9. | ALA4521157 | Table 1, cpd 2 | t1/2 | > | 2 | hr | ALA4383905 | hr | ||||
10. | ALA4521157 | Table 1, cpd 2 | t1/2 | > | 2 | hr | ALA4383904 | hr | ||||
11. | ALA4521157 | Table 1, cpd 2 | t1/2 | > | 2 | hr | ALA4383903 | hr | ||||
12. | ALA4521157 | Table 1, cpd 2 | t1/2 | = | 20 | min | ALA4383902 | hr | ||||
13. | ALA4521157 | Table 1, cpd 2 | t1/2 | = | 43 | min | ALA4383901 | hr | ||||
14. | ALA4521157 | Table 1, cpd 2 | t1/2 | = | 122 | min | ALA4383900 | hr | ||||
15. | ALA4521157 | Table 1, cpd 2 | Activity | 0 | ALA4383899 | Not Active | Mus musculus | |||||
16. | ALA4521157 | Table 1, cpd 2 | Activity | 0 | ALA4383898 | Not Active | Homo sapiens | |||||
17. | ALA4521157 | Table 1, cpd 2 | INH | 0 | ALA4383897 | Not Active | % | Homo sapiens | ||||
18. | ALA4521157 | Table 1, cpd 2 | IC50 | > | 1000 | nM | ALA4383896 | nM | Rattus norvegicus | |||
19. | ALA4521157 | Table 1, cpd 2 | IC50 | = | 36.5 | nM | ALA4383894 | 7.44 | nM | Rattus norvegicus | ||
20. | ALA4521157 | Table 1, cpd 2 | IC50 | = | 8.9 | nM | ALA4383895 | 8.05 | nM | Homo sapiens |