| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4522927 | 25 | IC50 | = | 85.16 | nM | ALA5137950 | 7.07 | nM | Homo sapiens | ||
| 2. | ALA4522927 | 25 | PPB | = | 99.6 | % | ALA4360774 | % | ||||
| 3. | ALA4522927 | 25 | PPB | = | 99.2 | % | ALA4360773 | % | ||||
| 4. | ALA4522927 | 25 | PPB | = | 99.7 | % | ALA4360772 | % | ||||
| 5. | ALA4522927 | 25 | INH | > | 30 | uM | ALA4360771 | uM | Homo sapiens | |||
| 6. | ALA4522927 | 25 | IC50 | > | 30 | uM | ALA4360769 | nM | Homo sapiens | |||
| 7. | ALA4522927 | 25 | IC50 | > | 30 | uM | ALA4360768 | nM | Homo sapiens | |||
| 8. | ALA4522927 | 25 | IC50 | > | 30 | uM | ALA4360767 | nM | Homo sapiens | |||
| 9. | ALA4522927 | 25 | IC50 | > | 30 | uM | ALA4360766 | nM | Homo sapiens | |||
| 10. | ALA4522927 | 25 | IC50 | > | 30 | uM | ALA4360765 | nM | Homo sapiens | |||
| 11. | ALA4522927 | 25 | IC50 | > | 30 | uM | ALA4360764 | nM | Homo sapiens | |||
| 12. | ALA4522927 | 25 | IC50 | = | 76 | nM | ALA4360763 | 7.12 | nM | Homo sapiens | ||
| 13. | ALA4522927 | 25 | IC50 | = | 47 | nM | ALA4360762 | 7.33 | nM | Homo sapiens | ||
| 14. | ALA4522927 | 25 | IC50 | = | 9.7 | nM | ALA4360761 | 8.01 | nM | Homo sapiens | ||
| 15. | ALA4522927 | 25 | t1/2 | = | 142 | min | ALA4360775 | hr | ||||
| 16. | ALA4522927 | 25 | t1/2 | = | 147 | min | ALA4360776 | hr | ||||
| 17. | ALA4522927 | 25 | Cmax | = | 3605 | ng/ml | ALA4360777 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 18. | ALA4522927 | 25 | AUC | = | 29116 | ng/mL.hr | ALA4360778 | ng.hr.mL-1 | ||||
| 19. | ALA4522927 | 25 | t1/2 | = | 4.55 | hr | ALA4360779 | hr | ||||
| 20. | ALA4522927 | 25 | F | = | 59.6 | % | ALA4360780 | % |
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