| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  Miransertib hydrochloride | 21a | F | = | 49 | % | ALA4478709 | % | ||||
| 2. | Miransertib hydrochloride | 21a | AUC | = | 2960 | hr.ng/ml | ALA4478708 | ng.hr.mL-1 | ||||
| 3. | Miransertib hydrochloride | 21a | Cmax | = | 258 | ng/ml | ALA4478707 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 4. | Miransertib hydrochloride | 21a | t1/2 | = | 7 | hr | ALA4478706 | hr | ||||
| 5. | Miransertib hydrochloride | 21a | Tmax | = | 4.3 | hr | ALA4478705 | hr | ||||
| 6. | Miransertib hydrochloride | 21a | F | = | 62 | % | ALA4478704 | % | ||||
| 7. | Miransertib hydrochloride | 21a | AUC | = | 5496 | hr.ng/ml | ALA4478703 | ng.hr.mL-1 | ||||
| 8. | Miransertib hydrochloride | 21a | Cmax | = | 198 | ng/ml | ALA4478702 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 9. | Miransertib hydrochloride | 21a | t1/2 | = | 17 | hr | ALA4478701 | hr | ||||
| 10. | Miransertib hydrochloride | 21a | Tmax | = | 8 | hr | ALA4478700 | hr | ||||
| 11. | Miransertib hydrochloride | 21a | Drug uptake | = | 27.4 | uM | ALA4478699 | uM | ||||
| 12. | Miransertib hydrochloride | 21a | Drug uptake | = | 35.8 | uM | ALA4478698 | uM | ||||
| 13. | Miransertib hydrochloride | 21a | Drug uptake | = | 9.6 | uM | ALA4478697 | uM | ||||
| 14. | Miransertib hydrochloride | 21a | Drug uptake | = | 21 | uM | ALA4478696 | uM | ||||
| 15. | Miransertib hydrochloride | 21a | Cp | = | 1 | uM | ALA4478695 | uM | ||||
| 16. | Miransertib hydrochloride | 21a | Cp | = | 2.7 | uM | ALA4478694 | uM | ||||
| 17. | Miransertib hydrochloride | 21a | Cp | = | 0.26 | uM | ALA4478693 | uM | ||||
| 18. | Miransertib hydrochloride | 21a | Cp | = | 2.1 | uM | ALA4478692 | uM | ||||
| 19. | Miransertib hydrochloride | 21a | INH | = | 42.5 | % | ALA4478691 | % | Mus musculus | |||
| 20. | Miransertib hydrochloride | 21a | INH | = | 50.5 | % | ALA4478690 | % | Mus musculus |
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