# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4525494 | 6e | CL free | = | 28.1 | L/hr/kg | ALA4428721 | mL.min-1.kg-1 | ||||
2. | ALA4525494 | 6e | CL | = | 1 | L/hr/kg | ALA4428720 | mL.min-1.kg-1 | ||||
3. | ALA4525494 | 6e | Activity | = | 4.9 | % | ALA4428719 | % | Homo sapiens | |||
4. | ALA4525494 | 6e | Activity | = | 2.4 | % | ALA4428718 | % | Homo sapiens | |||
5. | ALA4525494 | 6e | IC50 | > | 27 | uM | ALA4428717 | nM | Homo sapiens | |||
6. | ALA4525494 | 6e | IC50 | > | 27 | uM | ALA4428716 | nM | Homo sapiens | |||
7. | ALA4525494 | 6e | CLH | = | 33 | uL/min.mg | ALA4428715 | mL.min-1.g-1 | ||||
8. | ALA4525494 | 6e | CLH | < | 14 | uL/min.mg | ALA4428714 | mL.min-1.g-1 | ||||
9. | ALA4525494 | 6e | IC50 | = | 8.5 | nM | ALA4428713 | 8.07 | nM | Mus musculus | ||
10. | ALA4525494 | 6e | IC50 | = | 1.2 | nM | ALA4428712 | 8.92 | nM | Homo sapiens | ||
11. | ALA4525494 | 6e | IC50 | = | 23200 | nM | ALA4428711 | 4.63 | nM | Homo sapiens | ||
12. | ALA4525494 | 6e | IC50 | = | 15600 | nM | ALA4428710 | 4.81 | nM | Homo sapiens | ||
13. | ALA4525494 | 6e | IC50 | = | 4.8 | nM | ALA4428708 | 8.32 | nM | Homo sapiens | ||
14. | ALA4525494 | 6e | IC50 | = | 29200 | nM | ALA4428709 | 4.54 | nM | Homo sapiens |