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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4528475	1b	permeability	=	382	nm/s	ALA4410492			nm/s
2.	ALA4528475	1b	IC50	=	6.4	nM	ALA4410491	8.19		nM	Homo sapiens
3.	ALA4528475	1b	TGI	=	31	%	ALA4410490			%	Homo sapiens
4.	ALA4528475	1b	TGI	=	4.6	%	ALA4410489			%	Homo sapiens
5.	ALA4528475	1b	TGI	=	0.5	%	ALA4410488			%	Homo sapiens
6.	ALA4528475	1b	Activity		0		ALA4410487		Active		Mus musculus
7.	ALA4528475	1b	F	=	105.2	%	ALA4410486			%
8.	ALA4528475	1b	Vdss	=	261	ml/kg	ALA4410485			L.kg-1
9.	ALA4528475	1b	CL	=	74	ml/hr/kg	ALA4410484			mL.min-1.kg-1
10.	ALA4528475	1b	t1/2	>	8	hr	ALA4410483			hr
11.	ALA4528475	1b	MRT	=	4.28	hr	ALA4410482			hr
12.	ALA4528475	1b	AUC	=	14404.2	ng.hr/ml	ALA4410481			ng.hr.mL-1
13.	ALA4528475	1b	Cmax	=	2176.1	ng/ml	ALA4410480		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
14.	ALA4528475	1b	INH	=	-24	%	ALA4410479			%	Homo sapiens
15.	ALA4528475	1b	INH	=	10.6	%	ALA4410478			%	Homo sapiens
16.	ALA4528475	1b	INH	=	-10.7	%	ALA4410477			%	Homo sapiens
17.	ALA4528475	1b	INH	=	68	%	ALA4410476			%	Homo sapiens
18.	ALA4528475	1b	Stability	=	15	microL/min/mg	ALA4410475			microL/min/mg
19.	ALA4528475	1b	Stability	=	11	microL/min/mg	ALA4410474			microL/min/mg
20.	ALA4528475	1b	permeability	=	357	nm/s	ALA4410473			nm/s